Compare Pepcid vs. Pepto-Bismol
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids.
Pepto-Bismol (bismuth subsalicylate) can help for many stomach and intestinal problems, but may take longer to work compared to some other anti-diarrheal medicines.
- Most people can take Famotidine without any noticeable day-to-day side effects.
- Famotidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
- You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
- Available as both a generic and over-the-counter option, so it's pretty affordable.
- Few drug interactions.
- Pepto-Bismol (bismuth subsalicylate) works well to alleviate stomach and intestinal problems and doesn't have many side effects.
- Comes in easy to take chewable pills or liquid, if you do not like swallowing pills.
- Is inexpensive and available over the counter.
- Coupons are available. Speak to your doctor or pharmacist.
- Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Famotidine.
- Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Famotidine (H2 blockers).
- Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
- May not be as strong as other anti-diarrheal or antacid medications.
- Should not be used for more than 2 days if your diarrhea does not go away or if you have a fever.
- For symptoms other than diarrhea, should not be used for more than 7 days without your doctor's approval. Speak to your doctor if symptoms persist.
- Chewable tablet
- Chewable tablet
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- Hiding possible cancer
- Increased side effects
- Current kidney disease
- Allergic reaction
- Reye's syndrome
- Children or teenagers that have or are recovering from flu/flu-like symptoms or chickenpox
- Allergy to salicylates
- Aspirin allergy
- NSAID allergy
- Hearing problems
- Age 60 or older
- Drug Interactions
- Aspirin-containing medications