Compare Percocet vs. Acetaminophen with codeine
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats moderate to severe pain.
Percocet (Oxycodone / Acetaminophen) is the strongest prescription combination pain medicine for as needed pain relief, but make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.
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3.8/ 5 average rating with 1399 reviewsforPercocet
Treats mild to moderate pain.
Acetaminophen with codeine (acetaminophen / codeine) is a good option to treat pain when over-the-counter medicines aren't enough, but don't take too much acetaminophen (Tylenol) since it can hurt your liver.
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3.7/ 5 average rating with 581 reviewsforAcetaminophen with codeine
Upsides
- Combination pain medicine with an opioid component (oxycodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
- Provides quick relief for moderate to severe pain to improve quality of life.
- Generally considered stronger than Norco or other combination pain medicine for treating pain.
- Good for as-needed, short-term use, but may be helpful to manage more long-term pain problems if used at the appropriate doses and intervals.
- Lower rates of misuse compared to pure opioid medicines.
- Can help you fall asleep easier.
- Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relief in a single pill.
- Provides quick relief for mild to moderate pain.
- Good for as-needed pain and control.
- Generally well tolerated, especially if taken with food to lower risk of stomach upset.
- Lower rates of misuse compared to pure opioid medicines.
Downsides
- Dizziness and drowsiness is common, but your body may adjust.
- Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Percocet if you need.
- All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
- The non-opioid part of Percocet, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
- Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
- Avoid alcohol.
- Dizziness and drowsiness is common, but your body may adjust.
- Many people get constipated taking Acetaminophen with codeine (acetaminophen / codeine).
- All opioid containing medicines have the risk of addiction and withdrawal when used long-term.
- Acetaminophen (Tylenol) has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful since many over-the-counter medicines also have acetaminophen.
Used for
Dosage forms
- Pill
- Oral solution
- Pill
- Liquid
Price
Lowest price
$222.96
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$8.52
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Reviews
1399 reviews so far
70%
saidit'sworth it
49%
saiditworked well
15%
saidit'sa big hassle
Have you used Percocet (Oxycodone / Acetaminophen)?
Leave a review581 reviews so far
69%
saidit'sworth it
41%
saiditworked well
9%
saidit'sa big hassle
Have you used Acetaminophen with codeine (acetaminophen / codeine)?
Leave a reviewSide effects
The Percocet (Oxycodone / Acetaminophen) FDA package insert doesn’t have numbers about how common side effects are.
The Acetaminophen with codeine (acetaminophen / codeine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Death from liver failure
- Current liver disease
- Taking with alcohol
- Taking other medicines with acetaminophen
- Death from lack of oxygen to the body (respiratory depression)
- Age 65 or greater
- Higher dose
- People with not enough thyroid hormones
- History of lung problems
- Driving impairment
- Taking with alcohol
- Taking other medicines that make you less alert
- Age 65 or greater
- Tolerance and dependence
- Taking more than the prescribed dose
- Long-term use
- History of drug abuse
- Neonatal withdrawal syndrome
- Long-term use of opioids in mother
- Breastfeeding while taking Percocet (Oxycodone / Acetaminophen)
- Death from overdose (extended-release tablet)
- Children age 18 and younger
- Taking more than prescribed dose
- Mixing with alcohol or drugs that interact with Percocet (Oxycodone / Acetaminophen)
- Severe allergic reactions
- Low blood pressure
- Age 65 years or older
- Circulation problems
- Liver failure and death
- Alcohol use
- Taking over-the-counter medicines with acetaminophen
- History of liver disease
- High risk to children
- Use with other CNS depressants
- Use with alcohol
- Use with benzodiazepines
- Use with other opiates
- Severe allergic reaction