Compare perphenazine vs. Risperdal
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats schizophrenia.
Trilafon (perphenazine) is a good medicine for schizophrenia, but it can make you gain weight.
Helps control your thoughts and mood.
Risperdal (risperidone) is an effective medication in treating schizophrenia, mania, and irritability associated with autism; however, amongst other newer medications in its class, it's more likely to cause side effects, such weight gain and hormone problems.
●●●●●
3.4/ 5 average rating with 45 reviewsforRisperdal
Upsides
- Trilafon (perphenazine) can be much cheaper than other medicines.
- Trilafon (perphenazine) is less likely to cause heart problems or changes in blood pressure.
- Risperdal (risperidone) is effective at relieving psychotic symptoms, manic episodes, irritability, and aggressive behavior. It also lowers relapse rates in people with schizophrenia and people with irritability associated with autism.
- Less likely to cause heart problems compared to other antipsychotics.
- Compared to other antipsychotics, Risperdal (risperidone) causes less sedation and weight gain.
- A generic version available for pill, dissolving tablet, and liquid formulations.
Downsides
- You're more likely to gain weight.
- You can be more sensitive to temperature changes.
- You're more likely to catch colds and flu.
- Mild to moderate risk of Extrapyramidal Symptoms (EPS) - movement disorders that cause stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
- People taking Risperdal (risperidone) might have weight gain and problems with cholesterol or blood sugar.
- Compared to other antipsychotics, this medication has a higher risk of hormone problems that can cause nipples to leak and male breasts to grow abnormally large.
- You might need routine blood tests to check how the medicine is affecting your body.
- Risperdal (risperidone) takes 4 to 6 weeks for its full effects on thoughts and mood.
Used for
- Schizophrenia
- Bipolar I disorder (manic)
- Irritability associated with autistic disorder
- Post-traumatic stress disorder (PTSD)
- Tourette's Syndrome
- Behavioral symptoms associated with dementia
- Autism Spectrum Disorder
- Depression
Dosage forms
- Pill
- Pill
- Dissolving tablet
- Liquid
- Injection
Price
Lowest price
$34.24
Find instant savings near youLowest price
$531.18
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
Not enough review data.Leave a review
45 reviews so far
42%
saidit'sworth it
47%
saiditworked well
49%
saidit'sa big hassle
Have you used Risperdal (risperidone)?
Leave a reviewSide effects
The Trilafon (perphenazine) FDA package insert doesn’t have numbers about how common side effects are.
23possible side effects
- Sedation63%
- Increased appetite44%
- Fatigue31%
- Vomiting20%
- Common cold19%
- Constipation17%
- Cough17%
- Fever16%
- Involuntary urination16%
- Drooling12%
- Headache12%
- Hay fever12%
- Dry mouth10%
- Nasal congestion10%
- Nausea8%
- Upper respiratory tract infection8%
- Weight gain8%
- Tremor8%
- Dizziness8%
- Movement disorder8%
- Rash8%
- Increased saliva7%
- Thirst7%
Risks and risk factors
- Higher risk of death
- People age 65 or older with dementia and psychosis
- Difficulty controlling movements
- Higher risk for falls
- Sleepiness
- Drinking alcohol or taking narcotics
- Higher risk of infection
- Increased risk of death
- Elderly patients with dementia
- Neuroleptic malignant syndrome
- Heart problems
- History of heart problems
- Drug interactions
- Shaking and restlessness
- High doses of Risperdal (risperidone)
- Higher blood sugar and cholesterol and weight gain
- People with diabetes
- People with high cholesterol
- Driving impairment
- Alcohol
- Taking other medicines that make you less alert