Compare perphenazine vs. Zyprexa
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats schizophrenia.
Trilafon (perphenazine) is a good medicine for schizophrenia, but it can make you gain weight.
Helps control your thoughts and mood.
Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it's more likely to cause weight gain and sleepiness than other antipsychotics.
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3.7/ 5 average rating with 68 reviewsforZyprexa
Upsides
- Trilafon (perphenazine) can be much cheaper than other medicines.
- Trilafon (perphenazine) is less likely to cause heart problems or changes in blood pressure.
- Effective at relieving psychotic symptoms, manic episodes, and agitation in people with schizophrenia and bipolar disorder.
- Less likely to cause heart problems than other antipsychotics.
- Less likely to cause movement problems compared to older antipsychotics.
Downsides
- You're more likely to gain weight.
- You can be more sensitive to temperature changes.
- You're more likely to catch colds and flu.
- More likely to cause weight gain and increase cholesterol or blood sugar compared to other antipsychotics.
- Might make you more sleepy than some antipsychotics.
- Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive movements you can't control.
- You may need routine blood tests to check how the medicine is affecting your body..
Used for
Dosage forms
- Pill
- Pill
- Dissolving tablet
- Injection
Price
Lowest price
$32.66
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$641.59
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Reviews
Not enough review data.Leave a review
68 reviews so far
41%
saidit'sworth it
51%
saiditworked well
51%
saidit'sa big hassle
Have you used Zyprexa (olanzapine)?
Leave a reviewSide effects
The Trilafon (perphenazine) FDA package insert doesn’t have numbers about how common side effects are.
9possible side effects
- Drowsiness48%
- Weight gain28%
- Increased appetite28%
- Headache17%
- Fatigue14%
- Dizziness7%
- Dry Mouth7%
- Abdominal pain6%
- Pain in extremity5%
Risks and risk factors
- Higher risk of death
- People age 65 or older with dementia and psychosis
- Difficulty controlling movements
- Higher risk for falls
- Sleepiness
- Drinking alcohol or taking narcotics
- Higher risk of infection
- Increased risk of death
- Elderly patients with dementia
- Blood disorders
- Neuroleptic malignant syndrome
- Heart problems
- History of heart problems
- Drug interactions
- Shaking and restlessness
- Higher blood sugar, high cholesterol, and weight gain
- People with diabetes
- People with high cholesterol