Compare Prandimet vs. Precose

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lowers blood sugar.

Prandimet (metformin / repaglinide) effectively controls blood sugar levels for patients who are not controlled on either metformin or repaglinide alone.

Lowers blood sugar.

Precose (acarbose) helps lower your post-mealtime blood sugar levels, but it must be taken at the beginning of each main meal in order for it to be most effective.

  • Prandimet (metformin / repaglinide) combines 2 medications into one pill, which makes it easier to take.
  • Prandimet (metformin / repaglinide) is fast-acting and reaches full effect within an hour.
  • Precose (acarbose) helps control meal-time blood sugar levels without causing weight gain.
  • When used alone it doesn't normally cause blood sugar levels to be too low unlike other anti-diabetes medicines.
  • Safe to be used in people age 65 or older.
  • Has relatively few interactions with other medicines.
  • Prandimet (metformin / repaglinide) should not be used in those with liver or kidney problems.
  • Has to be taken with meals.
  • Should not be used in children under 18 years old.
  • May cause weight gain and low blood sugar.
  • Not a first choice medicine because it isn't as effective at lowering blood sugar compared to other treatment options.
  • Associated with bothersome side effects like excessive gas and diarrhea.
  • Relatively more expensive than other diabetes medicines.
  • Has to be taken three times a day with each meal.
  • Might cause episodes of low blood sugar when taken together with insulin or medicines that stimulate insulin release.
Used for
Dosage forms
  • Pill
  • Pill
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Side effects
6possible side effects
  • Digestive problems
  • Low blood sugar
  • Headache
  • Diarrhea
  • Nausea
  • Common cold
See more detailed side effects
3possible side effects
  • Excessive gas
  • Diarrhea
  • Stomach pain
See more detailed side effects
Risks and risk factors
  • Excess lactic acid
    • Kidney problems
    • Liver problems
    • Congestive heart failure
    • Using contrast dye for procedures
    • Surgery
    • Alcohol use
  • Low blood sugar (hypoglycemia)
    • Alcoholism
    • Changes in meal pattern
    • Changes in exercise
    • Insulin
    • Other antidiabetic medications
  • Interactions with other drugs
    • Taking certain medications that increase the amount of Prandimet (metformin / repaglinide)
  • Heart damage
    • Using Novolin or Humulin
  • Low vitamin B12 levels
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  • Low blood sugar
    • Using insulin or other medicines that stimulate insulin release
  • Kidney function
    • Those with kidney problems
  • Interactions with other medicines
    • Taking multiple medicines together
See more detailed risks and warnings