Compare Prandin vs. Starlix

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Prandin (repaglinide)

Prescription only

Starlix (nateglinide)

Prescription only
Lowers blood sugar.

Prandin (repaglinide) works quickly to lower blood sugar, especially during mealtimes. However, it can cause hypoglycemia (low blood sugar) if you are not consistent with your diet and exercise schedule.

Lowers blood sugar.

Starlix (nateglinide) can quickly lower your blood sugar, but needs to be timed with your meals.

Upsides
  • Quickly and effectively lowers blood sugar during meal times.
  • Less likely to cause hypoglycemia (low blood sugar) than Starlix (nateglinide).
  • Good first-choice if you cannot tolerate metformin or add-on therapy if your blood sugars are not controlled on metformin alone.
  • Can quickly lower blood sugar.
  • Good alternative if you have poor kidney function.
  • Can be safely used in people 65 and older.
  • Widely available in generic (cheaper) form.
Downsides
  • May cause some weight gain.
  • May cause hypoglycemia (low blood sugar).
  • Can frequently interfere with how other medicines work.
  • Not a good choice if you have poor kidney function, liver problems, or younger than 18 years old.
  • Take during mealtime.
  • May need to take as often as three times daily.
  • Can easily cause hypoglycemia (low blood sugar) if you don't maintain a consistent diet or exercise schedule.
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Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price
$16.81
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Lowest price
$27.72
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Reviews
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Side effects
20possible side effects
  • Low blood sugar
    31%
  • Headache
    11%
  • Sinusitis
    6%
  • Joint pain
    6%
  • Nausea
    5%
  • Diarrhea
    5%
  • Back pain
    5%
  • Swelling in arms and legs
    5%
  • Heart failure
    4%
  • Rhinitis
    3%
  • Constipation
    3%
  • Vomiting
    3%
  • Tingling, numbness, or burning sensation on the skin
    3%
  • Chest pain
    3%
  • Weight gain
    3%
  • Inflammation of the airways
    2%
  • Indigestion
    2%
  • Urinary tract infection
    2%
  • Tooth disorder
    2%
  • Allergy
    2%
See more detailed side effects
10possible side effects
  • Common cold
    11%
  • Back pain
    4%
  • Flu symptoms
    4%
  • Dizziness
    4%
  • Joint problems
    3%
  • Diarrhea
    3%
  • Accidental trauma
    3%
  • Inflammation of the airways
    3%
  • Coughing
    2%
  • Low blood sugar
    2%
See more detailed side effects
Risks and risk factors
  • Low blood sugar (hypoglycemia)
    • Alcoholism
    • Changes in meal pattern
    • Changes in exercise
    • Insulin
    • Other antidiabetic medications
    • Elderly
    • Bad liver or kidney function
  • Heart damage
    • use with NPH-insulin
See more detailed risks and warnings
  • Low blood sugar (hypoglycemia)
    • Changes in meal pattern
    • Changes in how much exercise you do
    • Taking other antidiabetic medications
    • Bad liver or renal function
See more detailed risks and warnings
Learn more about Prandin (repaglinide)
Learn more about Starlix (nateglinide)