Compare pravastatin vs. Lopid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Pravachol (pravastatin)

Prescription only

Lopid (gemfibrozil)

Prescription only
Lowers cholesterol.

Pravachol (pravastatin) can improve cholesterol, but it's not as strong as other statin medicines. It does cause fewer side effects and is safer for your kidneys and liver.

3.5/ 5 average rating with 426 reviewsforpravastatin
Lowers cholesterol and triglyceride levels.

Lopid (gemfibrozil) works well to lower triglycerides and bad cholesterol, but it may not be the best option if you're also on a statin drug.

Upsides
  • Compared to other statins, Pravachol (pravastatin) has fewer interactions with medicines.
  • Pravachol (pravastatin) is less likely to cause muscle and kidney damage than other statin medicines.
  • If you have liver problems, Pravachol (pravastatin) is the safest statin to use.
  • It's available as a generic.
  • Lopid (gemfibrozil) is available as a generic.
  • It can significantly lower your triglycerides and bad cholesterol (LDL), and raise your good cholesterol (HDL).
  • More effective and causes fewer side effects than non-statin cholesterol-lowering medicines.
Downsides
  • Pravachol (pravastatin) isn't as strong as other statins in lowering your cholesterol.
  • You'll still need to eat a low fat diet and exercise regularly to get the full benefit of Pravachol (pravastatin).
  • Since so many people use statin medications to treat their cholesterol, Lopid (gemfibrozil) isn't generally the first choice treatment to use since it can interact with statins.
  • Can be more expensive than some alternative medicines.
  • Need to take Lopid (gemfibrozil) twice a day, whereas other similar medications are only once a day.
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Reviews
426 reviews so far
54%
saidit'sworth it
44%
saiditworked well
19%
saidit'sa big hassle

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Side effects
20possible side effects
  • Muscle, joint or ligament/tendon pain    
    10%
  • Nausea, vomiting    
    7%
  • Diarrhea    
    7%
  • Headache    
    6%
  • Upper respiratory infection    
    6%
  • Chest pain    
    5%
  • Rash
    5%
  • Dizziness
    4%
  • Stuffy nose
    4%
  • Muscle damage
    4%
  • Flatulence    
    3%
  • Indigestion, heartburn    
    3%
  • Fatigue    
    3%
  • Cough
    3%
  • Increased liver enzymes
    3%
  • Abdominal swelling
    2%
  • Influenza
    2%
  • Muscle pain
    2%
  • Sore throat
    2%
  • Bile duct disease
    2%
See more detailed side effects
9possible side effects
  • Stomach and intestinal problems
    34%
  • Stomach upset
    20%
  • Abdominal pain
    10%
  • Diarrhea
    7%
  • Fatigue
    4%
  • Nausea or vomiting
    3%
  • Eczema
    2%
  • Rash
    2%
  • Feeling off balance
    2%
See more detailed side effects
Risks and risk factors
  • Muscle damage
    • Kidney disease
    • An underactive thyroid
    • Over age 65
    • Female gender
    • Taking other medicines to lower your cholesterol
  • Liver damage
    • Heavy alcohol use
    • History of chronic liver disease
  • Harm to fetus
    • Pregnancy
    • Breast feeding
  • Endocrine function
    • Spironolactone use
    • Cimetidine use
    • Ketoconazole use
See more detailed risks and warnings
  • Muscle pain
    • Taking Lopid (gemfibrozil) with statins
  • Liver problems
    • Past history of liver disease
  • Kidney problems
    • Kidney problems
  • Bleeding risk
    • Taking Lopid (gemfibrozil) with anticoagulants
  • Breastfeeding
  • Gallstones
See more detailed risks and warnings