Compare prednisone vs. Cimzia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Deltasone (prednisone)

Prescription only

Cimzia (certolizumab)

Prescription only
Calms down your immune system.

Deltasone (prednisone) is effective for controlling allergic reactions and conditions involving an overactive immune system. It can quickly make you feel better, but Deltasone (prednisone) can cause serious complications and side effects if taken for a long time.

3.5/ 5 average rating with 540 reviewsforprednisone
Calms the immune system and prevents joint damage.

Cimzia (certolizumab) effectively calms down your immune system, but you have to be comfortable receiving injections.

Upsides
  • Deltasone (prednisone) effectively treats a variety of conditions involving the immune system.
  • Can help improve energy and stimulate your appetite.
  • Works quickly to provide relief for swelling, rash, asthma attacks, and pain.
  • Good long-term treatment option for autoimmune disorders.
  • Deltasone (prednisone) is available in a generic form.
  • People taking Cimzia (certolizumab) for Crohn's disease, rheumatoid arthritis and other autoimmune conditions had greater clinical response compared to people who did not take Cimzia (certolizumab).
  • Compared to some other drugs used to treat autoimmune conditions, Cimzia (certolizumab) has not been associated with as many harmful effects during pregnancy and breastfeeding.
  • You can give yourself Cimzia (certolizumab) on your own at home rather than visiting a clinic or hospital.
  • After the initial dosing, you need to take Cimzia (certolizumab) every 4 weeks.
  • Cimzia (certolizumab) has been on the market for almost 10 years.
Downsides
  • Deltasone (prednisone) can cause unwanted side effects such as mood changes, trouble sleeping, and increase in blood pressure as well as blood sugar at higher doses.
  • Long-term use can cause problems to your skin, bones, eyes, and place you at a higher risk for infections.
  • If Deltasone (prednisone) is used for more than 2 weeks, you will need to work with a doctor to taper off the medicine by gradually decreasing the dose.
  • Deltasone (prednisone) can harm an unborn baby, so it's not a good option for pregnant women.
  • Cimzia (certolizumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, or had tuberculosis (TB) in the past.
  • Can in some cases cause bladder infections, rash and respiratory infections (cold or flu)
  • In rare cases, Cimzia (certolizumab) has been associated with cancers in children and adolescents.
  • Can increase your risk of side effects if you have a history of heart failure, nervous system conditions, or hepatitis B.
  • There's no generic available and it can be expensive.
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Used for
Dosage forms
  • Pill
  • Delayed release pill
  • Liquid
  • Injection
Price
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Reviews
540 reviews so far
59%
saidit'sworth it
45%
saiditworked well
20%
saidit'sa big hassle

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Side effects
The Deltasone (prednisone) FDA package insert doesn’t have numbers about how common side effects are.
4possible side effects
  • Infections
    38%
  • Upper airway infections
    20%
  • Urinary tract infections
    7%
  • Joint pain
    6%
See more detailed side effects
Risks and risk factors
  • Physicial Dependence
    • Taking high doses of Deltasone (prednisone) for a long period of time
    • Young children
    • Stress such as trauma, injury, or infection
  • Increased risk for infections
    • Taking other medicines that weaken the immune system
    • Taking Deltasone (prednisone) for a long time
    • Those who are not vaccinated against viral illnesses
    • Coming into contact with people who have viral illness
    • History of bacterial or viral conditions
  • Eye problems
    • Those with cataracts and/or glaucoma
    • History of herpes simplex in the eye
  • Changes in heart and kidney function
    • Those who had a recent heart attack
    • History of heart failure, high blood pressure, and kidney problems
  • Effects on bone
    • Taking Deltasone (prednisone) at high doses and/or for a long period of time
    • Infants and young children
    • Age 60 or older
  • Stomach problems
    • History of stomach bleeding
    • History of stomach ulcers
    • History of Ulcerative Colitis
    • Taking Deltasone (prednisone) with other medicines that can also cause stomach problems
See more detailed risks and warnings
  • Serious infections
    • Taking other immunosuppressant medications such as methotrexate or steroids
    • Age 65 or older
    • Active, chronic, or recurrent infection
    • Comorbidities
  • Cancers
    • Taking other immunosuppressant medications, such as azathiprine or 6-mercaptopurine, at the same time as Cimzia (certolizumab)
    • History of malignancy
    • Adolescent age
  • Heart problems
    • History of heart failure
  • Serious allergic reactions
  • Lower blood cell counts
  • Nervous system effects
    • Multiple sclerosis
    • Guillain-Barre syndrome
See more detailed risks and warnings