Compare Prezista vs. Crixivan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats HIV infection.

Prezista (darunavir) is one of the first-choices for treatment of HIV because it has fewer side-effects compared to other medicines that work like it.

Treats HIV infection.

Crixivan (indinavir) is a good alternative drug used with other medications to treat HIV, but is not a first-choice treatment because of its side effects and many drug interactions.

Upsides
  • Prezista (darunavir) is a good choice for those newly diagnosed HIV.
  • May be used in combination with other HIV medicines if you have been accidentally exposed to HIV by a needle-stick.
  • Available as a liquid solution and can be used for children as young as 3 years old.
  • Can be effective at treating HIV infection if other medicines have not worked.
Downsides
  • Need to take together with a booster like Norvir.
  • Doesn't work as well for those with longstanding HIV.
  • Can affect your cholestorol and blood sugar levels.
  • Crixivan (indinavir) interacts with many other drugs. Talk to your doctor or pharmacist before starting any new medications.
  • Crixivan (indinavir) can cause kidney stones so it's important to stay hydrated.
  • Crixivan (indinavir) might cause yellowing of the skin or eyes.
  • Crixivan (indinavir) can cause high cholesterol, triglyceride, and blood sugar levels.
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Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
Price
Lowest price
$1578.13
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Reviews
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Side effects
12possible side effects
  • Diarrhea
    14%
  • Headache
    7%
  • Nausea
    7%
  • Rash
    7%
  • Abdominal pain
    6%
  • Vomiting
    5%
  • Physical weakness
    3%
  • Loss of appetite
    2%
  • Abdominal swelling
    2%
  • Indigestion
    2%
  • Fatigue
    2%
  • Diabetes
    2%
See more detailed side effects
21possible side effects
  • Abdominal pain
    17%
  • Kidney stones
    12%
  • Nausea
    12%
  • Elevated serum bilirubin
    12%
  • Vomiting
    8%
  • Back pain
    8%
  • Headache
    5%
  • Itching
    4%
  • Diarrhea
    3%
  • Acid regurgitation
    3%
  • Anorexia
    3%
  • Dizziness
    3%
  • Metallic taste
    3%
  • Weakness/fatigue
    2%
  • Fever
    2%
  • Discomfort
    2%
  • Increased appetite
    2%
  • Indigestion
    2%
  • Yellowing of skin and eyes
    2%
  • Sleepiness
    2%
  • Cough
    2%
See more detailed side effects
Risks and risk factors
  • Liver damage
    • History of liver damage
    • Alcohol intake
  • Severe skin reactions
  • Sulfonamide allergy
  • Fat redistribution
    • HIV treatment
  • Immune recovery syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Diabetes
    • Use of protease inhibitors
    • Diabetes
See more detailed risks and warnings
  • New onset or worsened diabetes
    • Use of protease inhibitors
    • Diabetes
  • Hemolytic anemia
  • Liver damage
    • History of liver damage
  • Drug interactions
  • Kidney stones
    • Children
    • Dehydration
  • Fat redistribution
    • HIV treatment
See more detailed risks and warnings