Compare Prezista vs. Genvoya

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats HIV infection.

Prezista (darunavir) is one of the first-choices for treatment of HIV because it has fewer side-effects compared to other medicines that work like it.

Treats HIV infection.

Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir) is a convenient 4-in-1 medication. It's one of the first choices used to treat HIV infections and contains a newer medication that's safer for your kidneys and bones.

Upsides
  • Prezista (darunavir) is a good choice for those newly diagnosed HIV.
  • May be used in combination with other HIV medicines if you have been accidentally exposed to HIV by a needle-stick.
  • Available as a liquid solution and can be used for children as young as 3 years old.
  • First-choice treatment for HIV infections.
  • One tablet contains four different HIV medications and is only taken once daily.
  • Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir) has fewer side effects (headache, nausea, fatigue, diarrhea), and is safer on your kidneys and bones than Stribild.
Downsides
  • Need to take together with a booster like Norvir.
  • Doesn't work as well for those with longstanding HIV.
  • Can affect your cholestorol and blood sugar levels.
  • Should be taken with food.
  • Can increase cholesterol levels.
  • Can interact with many other drugs.
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Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
Price
Lowest price
$1801.63
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Lowest price
$3306.82
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Reviews
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Side effects
12possible side effects
  • Diarrhea
    14%
  • Headache
    7%
  • Nausea
    7%
  • Rash
    7%
  • Abdominal pain
    6%
  • Vomiting
    5%
  • Physical weakness
    3%
  • Loss of appetite
    2%
  • Abdominal swelling
    2%
  • Indigestion
    2%
  • Fatigue
    2%
  • Diabetes
    2%
See more detailed side effects
4possible side effects
  • Nausea
    10%
  • Diarrhea
    7%
  • Headache
    6%
  • Fatigue
    5%
See more detailed side effects
Risks and risk factors
  • Liver damage
    • History of liver damage
    • Alcohol intake
  • Severe skin reactions
  • Sulfonamide allergy
  • Fat redistribution
    • HIV treatment
  • Immune recovery syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Diabetes
    • Use of protease inhibitors
    • Diabetes
See more detailed risks and warnings
  • Lactic acidosis | Enlarged, fatty liver
    • Liver disease
    • Women
    • Obesity
  • Worsening hepatitis B infection
    • Hepatitis B Virus infection
  • Kidney damage
    • History of kidney damage
    • Taking other medicines that can harm the kidneys
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Drug interactions
    • Taking medicines that interact with Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir)
See more detailed risks and warnings
Learn more about Prezista (darunavir)
Learn more about Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir)