Compare Prezista vs. Kaletra
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats HIV infection.
Prezista (darunavir) is one of the first-choices for treatment of HIV because it has fewer side-effects compared to other medicines that work like it.
Treats HIV infection.
Kaletra (lopinavir / ritonavir) is not commonly used to treat HIV because of its side effects and the number of pills you have to take daily.
Upsides
- Prezista (darunavir) is a good choice for those newly diagnosed HIV.
- May be used in combination with other HIV medicines if you have been accidentally exposed to HIV by a needle-stick.
- Available as a liquid solution and can be used for children as young as 3 years old.
- Kaletra (lopinavir / ritonavir) can be taken once or twice daily.
- Tablets can be taken with or without food.
- An oral solution is available if tablets are hard to swallow.
Downsides
- Need to take together with a booster like Norvir.
- Doesn't work as well for those with longstanding HIV.
- Can affect your cholestorol and blood sugar levels.
- Has more side-effects compared to newer medicines that work like it.
- You may have to take up to 4 tablets to meet your required daily dose.
- Interacts with many other medicines and supplements.
- Can increase your risk for a heart attack.
Used for
- HIV infection
- HIV prevention
Dosage forms
- Pill
- Liquid
- Pill
- Liquid
Price
Lowest price
$2053.12
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$173.11
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Reviews
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Side effects
12possible side effects
- Diarrhea14%
- Headache7%
- Nausea7%
- Rash7%
- Abdominal pain6%
- Vomiting5%
- Physical weakness3%
- Loss of appetite2%
- Abdominal swelling2%
- Indigestion2%
- Fatigue2%
- Diabetes2%
35possible side effects
- Diarrhea20%
- Upper respiratory tract infection14%
- Nausea10%
- Fatigue and weakness8%
- Lower respiratory tract infection8%
- Vomiting7%
- High cholesterol7%
- Bone, joint and back pain7%
- Abdominal pain6%
- High fats6%
- Headaches including migraines6%
- Hepatitis and changes in liver function tests4%
- Insomnia4%
- Anxiety4%
- Skin rashes4%
- Inflammation in the stomach or intestines3%
- Skin allergies, hives and facial swelling3%
- Skin infections3%
- Anemia2%
- Decreased white blood cells2%
- Indigestion2%
- Pancreatitis2%
- Acid reflux2%
- Hemorrhoids2%
- Weight loss2%
- Loss of appetite2%
- Muscle pain2%
- Nerve damage2%
- Dizziness2%
- Erectile dysfunction2%
- Menstrual bleeding problems2%
- Changes in fat distribution2%
- Eczema2%
- Night sweats2%
- High blood pressure2%
Risks and risk factors
- Liver damage
- History of liver damage
- Alcohol intake
- Severe skin reactions
- Sulfonamide allergy
- Fat redistribution
- HIV treatment
- Immune recovery syndrome
- HIV
- Exposure to other infections
- Start of a new HIV medication
- Change in HIV therapy
- Diabetes
- Use of protease inhibitors
- Diabetes
- Liver damage
- History of liver damage
- Hepatitis B or C
- Heart (atrioventricular) block
- Use with other QT or PR prolonging drugs
- History of heart disease
- Low potassium levels
- Immune recovery syndrome
- HIV
- Exposure to other infections
- Start of a new HIV medication
- Change in HIV therapy
- Fat redistribution
- New or worsening diabetes
- Use of protease inhibitors
- Diabetes
- Pancreatitis
- Advanced HIV disease
- History of pancreatitis