Compare Provera vs. Vivelle-Dot
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Regulates your menstrual cycle and supplements estrogen treatments for menopause.
Provera (Medroxyprogesterone) works well to regulate your menstrual cycle and stop irregular bleeding. It also protects the uterus from estrogen's harmful effects.
Relieves menopausal symptoms.
Vivelle-Dot (Estradiol patch) is an estrogen patch that may be easier and more convenient to use than the pill or gel form.
Upsides
- Provera (Medroxyprogesterone) can be used to treat multiple hormone problems in women.
- After menopause, taking estrogen raises your risk of uterine cancer. However, taking progesterone, like in Provera (Medroxyprogesterone), along with estrogen gives you the positive effects of estrogen, but also prevents it from damaging your uterus.
- Women taking an estrogen/progestin combination medications have a lower risk of uterine cancer.
- Good choice if you want to avoid daily dosing of the pill or gel form.
- Available in wider variety of strengths compared to other estrogen patches.
Downsides
- You can't take Provera (Medroxyprogesterone) if you've had a hysterectomy (your uterus removed). You also can't take it if you're pregnant or breastfeeding, have unusual vaginal bleeding, or have a history of blood clots, certain kinds of cancer, stroke, heart attack, liver problems, or bleeding problems.
- Other estrogen patches are dosed once weekly and may be more convenient than Vivelle-Dot (Estradiol patch).
- Patches can fall off.
- Estrogen therapy is associated with serious risks for uterine cancer, breast cancer, and blood clots. Don't start treatment until you have had a thorough discussion of the risks and benefits with your doctor.
Used for
- Amenorrhea
- Abnormal uterine bleeding
- Prevention of uterine cancer in women taking estrogen
- Endometriosis
- Premenstrual syndrome
- Breast cancer
- Uterine cancer
- Pelvic congestion syndrome
- Birth control (male)
- Hirsutism
- Loss of appetite
- Osteoporosis
- Renal cell carcinoma
- Hot flashes
- Vaginal dryness and inflammation
- Low estrogen
- Prevention of osteoporosis in menopausal women
Dosage forms
- Pill
- Patch
Price
Lowest price
$9.24
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$28.86
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Side effects
The Provera (Medroxyprogesterone) FDA package insert doesn’t have numbers about how common side effects are.
20possible side effects
- Headache26%
- Breast pain13%
- Back pain11%
- Menstrual bleeding11%
- Influenza8%
- Common cold8%
- Nausea5%
- Pain5%
- Sinus infection5%
- Lung infection5%
- Neck pain5%
- Limb pain5%
- Nasal congestion5%
- Joint pain4%
- Depression3%
- Constipation2%
- Flu-like symptoms2%
- Sinus headache2%
- Anxiety2%
- Trouble sleeping2%
Risks and risk factors
- Breast cancer
- Personal or family history of breast cancer
- Ovarian cancer
- Family history of ovarian cancer
- Increased risk of blood clots and stroke
- Personal or family history of blood clots
- Smoking
- Obesity
- Hypertension
- Diabetes
- High cholesterol
- Systemic lupus erythematosus (SLE)
- Depression
- History of depression
- Liver problems
- History of liver problems
- Harm to fetus
- Women of childbearing age
- Uterine cancer
- Using estrogen for more than one year
- Breast cancer
- Personal or family history of breast cancer
- Using estrogen for more than one year
- Increased risk of blood clots and stroke
- Personal or family history of blood clots
- Smoking
- Obesity
- Systemic lupus erythematosus (SLE)
- Increased risk of heart disease
- Smoking
- Obesity
- High blood pressure
- High blood sugar
- High cholesterol
- Age 50 or older
- Dementia
- Age 65 or older
- Inflammation of pancreas
- High levels of triglycerides