Compare Provigil vs. Desoxyn

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Provigil (modafinil)

Prescription only

Desoxyn (methamphetamine)

Prescription only
Improves alertness.

Provigil (modafinil) is effective in improving alertness, but it interacts with some medicines and shouldn't be used long-term.

4.2/ 5 average rating with 28 reviewsforProvigil
Helps you focus and lose weight.

Desoxyn (methamphetamine) effectivly treats ADHD and obesity, but should not be used for long-term treatment.

4.4/ 5 average rating with 19 reviewsforDesoxyn
Upsides
  • Provigil (modafinil) is a nonstimulant medication that improves alertness.
  • Provigil (modafinil) is available in a cheaper, generic version.
  • Provigil (modafinil) is good at decreasing excessive sleepiness in shift work sleep disorder.
  • If you need to sleep in the daytime, this medication won't effect you.
  • Is a first-choice treatment for ADHD in both adults and children.
  • Available as a generic, so it is cheaper than other brand name medications to treat ADHD.
Downsides
  • Provigil (modafinil) can be habit forming, so it shouldn't be used for long-term treatment.
  • Provigil (modafinil) is not a good choice if you have liver problems.
  • May not be a good option if you are taking hormonal contraception like birth control pills.
  • Desoxyn (methamphetamine) is habit-forming and can lead to physical dependence.
  • Not carried by all pharmacies, so you may have a hard time getting this medication.
  • If you want to stop taking this medicine, talk to your doctor since suddenly stopping can cause withdrawal symptoms.
  • You'll have to check-in with your doctor often and get a new prescription monthly.
  • Only lowers appetite for the first few weeks.
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Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
28 reviews so far
82%
saidit'sworth it
71%
saiditworked well
4%
saidit'sa big hassle

Have you used Provigil (modafinil)?

Leave a review
19 reviews so far
84%
saidit'sworth it
79%
saiditworked well
11%
saidit'sa big hassle

Have you used Desoxyn (methamphetamine)?

Leave a review
Side effects
25possible side effects
  • Headache
    34%
  • Nausea
    11%
  • Nervousness
    7%
  • Stuffy nose
    7%
  • Back pain
    6%
  • Diarrhea
    6%
  • Indigestion
    5%
  • Difficulty sleeping
    5%
  • Anxiety
    5%
  • Dizziness
    5%
  • Flu symptoms
    4%
  • Dry mouth
    4%
  • Loss of appetite
    4%
  • Throat inflammation
    4%
  • Chest pain
    3%
  • High blood pressure
    3%
  • Fast heart beat
    2%
  • Palpitation
    2%
  • Dilation of blood vessels
    2%
  • Constipation
    2%
  • Abnormal liver function
    2%
  • Depression
    2%
  • Burning/tingling sensation
    2%
  • Drowsiness
    2%
  • Lung disorder
    2%
See more detailed side effects
The Desoxyn (methamphetamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Serious allergic reactions
    • Allergy to Provigil (modafinil)
  • Heart problems
    • History of heart problems
  • Increased side effects
    • Current kidney problems
    • Current liver problems
  • Driving impairment
    • Taking with alcohol or drugs
See more detailed risks and warnings
  • Serious or life-threatening cardiovascular events
    • History of heart problems
  • Abuse and dependence
    • History of drug abuse
  • Aggressive behavior and psychosis
    • History of psychotic episodes
    • History of Bipolar Disorder
  • Long-term growth suppression
    • Children
  • Seizures
    • History of seizures
  • Drug interactions
    • Taking MAO inhibitors and other serotonergic agents, as well as other medicines that can increase blood pressure
See more detailed risks and warnings