Compare Relafen vs. Acetaminophen with codeine
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Relieves pain and inflammation.
Relafen (nabumetone) works well for relieving pain and inflammation, but may take up to a week to kick in.
Treats mild to moderate pain.
Acetaminophen with codeine (acetaminophen / codeine) is a good option to treat pain when over-the-counter medicines aren't enough, but don't take too much acetaminophen (Tylenol) since it can hurt your liver.
●●●●●
3.7/ 5 average rating with 581 reviewsforAcetaminophen with codeine
Upsides
- Relafen (nabumetone) is good for relieving pain and inflammation from osteoarthritis and rheumatoid arthritis.
- Usually taken only once a day, while other NSAIDS need to be taken a few times a day for the same effect.
- Relafen (nabumetone) causes less stomach upset and overall side effects than other NSAIDs, like ibuprofen and naproxen.
- Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relief in a single pill.
- Provides quick relief for mild to moderate pain.
- Good for as-needed pain and control.
- Generally well tolerated, especially if taken with food to lower risk of stomach upset.
- Lower rates of misuse compared to pure opioid medicines.
Downsides
- Relafen (nabumetone) does not work as quickly as other NSAIDs.
- Relafen (nabumetone), like other NSAIDS, is not safe for pregnant women and people who are age 60 or older.
- Relafen (nabumetone) can cause serious complications including stomach bleeding and kidney problems if taken for a long period of time.
- The safety and effectiveness of Relafen (nabumetone) for children are not known so they should not take it.
- Dizziness and drowsiness is common, but your body may adjust.
- Many people get constipated taking Acetaminophen with codeine (acetaminophen / codeine).
- All opioid containing medicines have the risk of addiction and withdrawal when used long-term.
- Acetaminophen (Tylenol) has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful since many over-the-counter medicines also have acetaminophen.
Used for
- Rheumatoid arthritis
- Osteoarthritis
- Soft tissue injury
Dosage forms
- Pill
- Pill
- Liquid
Price
Lowest price
$11.92
Find instant savings near youLowest price
$8.61
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
Not enough review data.Leave a review
581 reviews so far
69%
saidit'sworth it
41%
saiditworked well
9%
saidit'sa big hassle
Have you used Acetaminophen with codeine (acetaminophen / codeine)?
Leave a reviewSide effects
The Acetaminophen with codeine (acetaminophen / codeine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Heart attack and stroke
- History of heart problems
- Taking Relafen (nabumetone) for a long period of time
- Stomach bleeding
- History of stomach bleeding and/or ulcers
- Age 60 or older
- Taking aspirin, other NSAIDs, steroids, or blood thinners
- Drinking alcoholic beverages
- Smoking
- Taking the medicine for a long period of time
- People with poor general health
- Severe allergic reaction
- Asthma
- Nasal polyps
- Aspirin allergy
- NSAID allergy
- Kidney damage
- Kidney disease
- Heart failure
- Liver disease
- Taking certain high blood pressure medications
- Age 60 or older
- Taking the medicine for a long period of time
- Harm to fetus
- Pregnant women
- Women who want to or can become pregnant
- Heart-related complications
- Recent heart surgery or heart attack
- History of high blood pressure
- History of heart failure
- Liver failure and death
- Alcohol use
- Taking over-the-counter medicines with acetaminophen
- History of liver disease
- High risk to children
- Use with other CNS depressants
- Use with alcohol
- Use with benzodiazepines
- Use with other opiates
- Severe allergic reaction