Compare Remeron vs. Elavil

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Remeron (mirtazapine)

Prescription only

Elavil (amitriptyline)

Prescription only
Improves mood.

Remeron (mirtazapine) improves your mood and helps you sleep better, but can cause more weight gain than any other antidepressant.

3.3/ 5 average rating with 152 reviewsforRemeron
Improves mood.

Elavil (amitriptyline) regulates mood and treats nerve pain, but has more side effects than alternatives.

3.3/ 5 average rating with 134 reviewsforElavil
Upsides
  • Effective at relieving some depression symptoms.
  • Starts to work more quickly than most antidepressants.
  • Can help you fall asleep if you have trouble sleeping.
  • Can also help relieve anxiety.
  • Good option if you are underweight or frail, because it can help you gain weight.
  • Available as a generic.
  • Elavil (amitriptyline) works well to treat nerve pain and is non-habit forming.
Downsides
  • Makes you more tired than other antidepressants.
  • More likely to cause minor weight gain (1-5 pounds) and raise cholesterol than any other antidepressant.
  • Elavil (amitriptyline) has more bothersome side effects than other antidepressants.
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Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Pill
Price
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Reviews
152 reviews so far
45%
saidit'sworth it
39%
saiditworked well
26%
saidit'sa big hassle

Have you used Remeron (mirtazapine)?

Leave a review
134 reviews so far
53%
saidit'sworth it
36%
saiditworked well
25%
saidit'sa big hassle

Have you used Elavil (amitriptyline)?

Leave a review
Side effects
17possible side effects
  • Sleepiness
    54%
  • Dry mouth
    25%
  • Increased appetite  
    17%
  • Increased appetite
    17%
  • Constipation
    13%
  • Weight gain
    12%
  • Lack of energy
    8%
  • Dizziness
    7%
  • Flu syndrome
    5%
  • Abnormal dreams
    4%
  • Abnormal thinking
    3%
  • Back pain
    2%
  • Swelling in limbs
    2%
  • Muscle pain
    2%
  • Tremor
    2%
  • Confusion
    2%
  • Urinary frequency
    2%
See more detailed side effects
The Elavil (amitriptyline) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Heart problems
    • History of heart problems
    • History of liver problems
    • Higher dose
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
  • Weight gain
  • Blood disorders
See more detailed risks and warnings
  • Suicidal thoughts or behavior
    • Age 24 years or younger
  • Mania
    • History of bipolar disorder
    • At risk for bipolar disorder
  • Heart problems
    • History of cardiovascular disease
  • Dizziness and falls
    • Age 65 years or older
    • Taking medicines to control blood pressure
  • Dehydration
    • Age 65 years or older
See more detailed risks and warnings