Compare Renova vs. minocycline

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Renova (Tretinoin)

Prescription only

Solodyn (minocycline)

Prescription only
Treats acne and sun damage.

Renova (Tretinoin) isn't a cure for fine lines and wrinkles, but it's clinically proven to improve them.

3.1/ 5 average rating with 58 reviewsforRenova
Treats bacterial infections.

Solodyn (minocycline) is effective in treating a variety of bacterial infections such as acne, but it can cause permanent tooth staining, especially in an unborn baby and those who are age 8 or younger.

4.0/ 5 average rating with 17 reviewsforminocycline
Upsides
  • You only need to apply it once a day, usually in the evening.
  • Most people who reported having skin irritation said that it was mild.
  • Part of a complete program to help you take better care of your skin.
  • May be taken with or without food.
  • Solodyn (minocycline) is used in combination with other medications to treat severe acne.
  • Available as a generic form.
  • Solodyn (minocycline) is less likely to cause sunburn than other tetracycline antibiotics.
  • Can be a good alternative treatment for certain infections when penicillin can't be used.
Downsides
  • It may take up to 6 months to see the full benefit for facial wrinkles.
  • Not a good choice for women who want to become or are pregnant
  • Can change the color and texture of your skin if used long-term.
  • You need to be careful about avoiding any sunlight or artificial tanning while using it.
  • It doesn't work for deep wrinkles.
  • It can make birth control pills less effective, so barrier methods of birth control like condoms or diaphragms should be used while on Solodyn (minocycline).
  • Can permanently discolor your teeth, mouth, gums and skin. This is more common for pregnant women in their last half of pregnancy, infants, and children 8 and younger.
  • Your skin may be more sensitive to the sun and your chances of getting sunburned are higher.
  • May cause dizziness and affect your driving ability.
  • Not a good option for pregnant women since it can slow down the bone development of a fetus (unborn baby).
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Used for
Dosage forms
  • Cream, gel, or ointment
  • Pill
  • Extended-release pill
Price
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Reviews
58 reviews so far
41%
saidit'sworth it
28%
saiditworked well
28%
saidit'sa big hassle

Have you used Renova (Tretinoin)?

Leave a review
17 reviews so far
53%
saidit'sworth it
59%
saiditworked well
18%
saidit'sa big hassle

Have you used Solodyn (minocycline)?

Leave a review
Side effects
4possible side effects
  • Mild skin reactions
    100%
  • Severe local irritation
    7%
  • Any side effect
    4%
  • Skin hypo- or hyperpigmentation
    2%
See more detailed side effects
The Solodyn (minocycline) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Skin irritation
    • Using other medicines or products that irritate the skin
    • Eczema
    • Extreme temperatures (hot or cold)
  • Sun sensitivity
  • Allergic reactions
    • Allergy to fish or fish products
  • Harm to fetus
See more detailed risks and warnings
  • Yellowing of teeth
    • Age 8 or younger
    • Women in their last half of pregnancy
    • Infants
    • Using Solodyn (minocycline) for a long period of time
  • Decreased effectiveness of oral birth control pills
    • Using oral birth control pills
  • New infection
    • Using Solodyn (minocycline) for a long period of time
  • Sunburn
  • Harm to fetus (unborn baby)
    • Women who can potentially or want to become pregnant
    • Pregnant women
See more detailed risks and warnings