Compare Requip vs. Azilect

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Requip (Ropinirole)

Prescription only

Azilect (rasagiline)

Prescription only
Helps with movement problems.

Requip (Ropinirole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.

Treats Parkinson's disease.

Azilect (rasagiline) is one of the recommended medicines to treat Parkinson's disease. It is now available in generic, which makes it more affordable for people without insurance.

Upsides
  • In studies, Requip (Ropinirole) when taken by itself or with other medicines, was effective in lowering movement fluctuations for people with Parkinson's disease.
  • Requip (Ropinirole) is sometimes preferred over other medicines that treat Parkinson's disease in older people since it causes fewer movement and mental fluctuations.
  • Is effective for treating restless leg syndrome.
  • Available in a short-acting and a long-acting form.
  • Azilect (rasagiline) is one of the go-to medicines for Parkinson's disease. It can be used in early and late stages of the disease.
  • Taking Azilect (rasagiline) by itself can help slow down Parkinson's disease, but it works better when it's given with other medicines.
  • Azilect (rasagiline) is available as generic as well as brand name, so there are usually lower out-of-pocket costs for you with insurance.
Downsides
  • Requip (Ropinirole) isn't a first-choice treatment for Parkinson's disease. It can be used by itself, but it's usually used with other medicines.
  • Requip (Ropinirole) can cause hallucinations in older people.
  • Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
  • You can't suddenly stop taking Requip (Ropinirole). You'll have to slowly lower your dose, especially if you've been using it for a long time.
  • It can cause unusual cravings and changes in behavior in some people.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
Price
Lowest price
$25.32
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Lowest price
$170.42
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Reviews
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Side effects
49possible side effects
  • Dyskinesia
    34%
  • Nausea
    30%
  • Dizziness
    26%
  • Adverse events
    24%
  • Somnolence
    20%
  • Headache
    17%
  • Falls
    10%
  • Hallucinations
    10%
  • Abdominal pain
    9%
  • Confusion
    9%
  • Upper respiratory tract infection
    9%
  • Hallucination
    8%
  • Increased sweating
    7%
  • Increased drug level
    7%
  • Vomiting
    7%
  • Arthralgia
    7%
  • Abdominal pain/discomfort
    6%
  • Adverse reactions
    6%
  • Tremor
    6%
  • Constipation
    6%
  • Anxiety
    6%
  • Urinary tract infection
    6%
  • Orthostatic hypotension
    5%
  • Dry mouth
    5%
  • Pain
    5%
  • Hypokinesia
    5%
  • Paresthesia
    5%
  • Diarrhea
    5%
  • Amnesia
    5%
  • Nervousness
    5%
  • Vertigo
    4%
  • Edema peripheral
    4%
  • Back pain
    3%
  • Hypertension
    3%
  • Syncope
    3%
  • Paresis
    3%
  • Arthritis
    3%
  • Abnormal dreaming
    3%
  • Dyspnea
    3%
  • Fall/injury
    2%
  • Hypotension
    2%
  • Dysphagia
    2%
  • Flatulence
    2%
  • Increased saliva
    2%
  • Weight decrease
    2%
  • Anemia
    2%
  • Pyuria
    2%
  • Urinary incontinence
    2%
  • Diplopia
    2%
See more detailed side effects
46possible side effects
  • Difficulty controlling movement
    18%
  • Headache
    14%
  • Accidental injury
    12%
  • Nausea
    12%
  • Falls
    11%
  • Weight loss
    9%
  • Constipation
    9%
  • Low blood pressure
    9%
  • Joint pain
    8%
  • Indigestion
    7%
  • Dizziness
    7%
  • Swelling in arms and legs
    7%
  • Vomiting
    7%
  • Dry mouth
    6%
  • Rash
    6%
  • Sleepiness
    6%
  • Depression
    5%
  • Flu-like symptoms
    5%
  • Abdominal pain
    5%
  • Loss of appetite
    5%
  • Diarrhea
    5%
  • Bruising
    5%
  • Tingling or prickling sensation
    5%
  • Back pain
    4%
  • Cough
    4%
  • Trouble sleeping
    4%
  • Cold or flu
    4%
  • Unusual dreams
    4%
  • Hallucinations
    4%
  • Eyelid problems
    3%
  • Fever
    3%
  • Stomach infection
    3%
  • Stuffy nose
    3%
  • Movement coordination problems
    3%
  • Shortness of breath
    3%
  • Infections
    3%
  • Neck pain
    3%
  • Sweating
    3%
  • Tendon swelling
    3%
  • Uncontrollable muscle movements
    3%
  • Arthritis
    2%
  • Weakness
    2%
  • Gum swelling
    2%
  • Excessive bleeding
    2%
  • Hernia
    2%
  • Muscle weakness
    2%
See more detailed side effects
Risks and risk factors
  • Impulse control problems
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Low blood pressure
    • Taking blood pressure-lowering medicines
  • Worsening kidney function
    • Current kidney problems
  • Skin cancer
    • Parkinson's disease
  • Hallucinations
    • Age 65 years or older
See more detailed risks and warnings
  • Increased blood pressure
    • Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats
  • Serotonin syndrome
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    • ADHD medicines
    • Triptans
    • dextromethorphan
    • pseudoephedrine
  • Falling asleep during the day
    • Taking other medicines for Parkinson's disease
  • Low blood pressure
  • Movement problems
    • Taking other medicines for Parkinson's disease
  • Lack of impulse control
    • Taking other medicines for Parkinson's disease
See more detailed risks and warnings
Learn more about Requip (Ropinirole)
Learn more about Azilect (rasagiline)