Compare Restoril vs. doxepin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Restoril (Temazepam)

Prescription only

doxepin

Prescription only
Helps you relax and sleep.

Restoril (Temazepam) is a good short-term option to help you sleep, but it shouldn't replace good sleep habits.

3.9/ 5 average rating with 51 reviewsforRestoril
Treats depression and anxiety.

doxepin can treat depression and anxiety, but it's not a first choice medication because of its many side effects.

Upsides
  • Helps you fall asleep and stay asleep.
  • Can be helpful to reduce anxiety.
  • Shouldn't make you drowsy the next day as long as you're using normal doses of it.
  • doxepin has been consistently shown to improve symptoms of depression and anxiety.
  • doxepin has been used to treat depression for over forty years.
Downsides
  • Can be habit-forming, meaning you'll start to rely on Restoril (Temazepam) to sleep.
  • Your body can get used to Restoril (Temazepam) and it may not work as well long-term.
  • It's not recommended for people age 65 years or older.
  • Can't be used by pregnant women since it'll cause harm to the baby.
  • If it's used everyday for more than 2 to 4 weeks and you decide to stop taking Restoril (Temazepam), you'll need to work with your doctor to slowly get off the drug to avoid extra side effects.
  • doxepin can make you very sleepy. Try taking it at bedtime if you need to be alert during the day.
  • You shouldn't drink alcohol with doxepin. It can worsen side effects like drowsiness.
  • You have to take it daily, especially if you are feeling better, for the medicine to do its job.
  • It can have more side effects than other antidepressants, like weight gain and increased appetite, decreased libido, and sleepiness.
  • It's not unusual for people to try different antidepressants until they find one that works for them.
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Used for
Dosage forms
  • Pill
  • Pill
  • Liquid
Price
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Reviews
51 reviews so far
65%
saidit'sworth it
55%
saiditworked well
16%
saidit'sa big hassle

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Side effects
The Restoril (Temazepam) FDA package insert doesn’t have numbers about how common side effects are.
The doxepin FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Tolerance and dependence
    • Taking more than the prescribed dose
    • Taking longer than 4 weeks
    • History of drug abuse
  • Withdrawal
    • Long-term use
  • Harm to fetus
    • Women of childbearing age
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
  • Memory problems
  • Falls
    • Taking with alcohol
    • Taking with other drugs that acts in the brain
    • Age 65 or older
See more detailed risks and warnings
  • Suicidal thoughts or behavior
    • Age 24 years or under
  • Unmasking of bipolar disorder
    • Bipolar disorder
  • Serotonin syndrome
    • Taking MAOIs (monoamine oxidase inhibitors)
  • Heart problems
    • History of heart disease
    • Adults over 65
    • Electrolyte imbalance
  • Sleepiness
    • Adults 65 years or older
    • Taking other medicines that cause drowsiness (antihistamines, sleep medications, narcotic pain medications)
    • Alcohol
  • Dizziness and falls
    • Age 65 years or older
See more detailed risks and warnings