Compare Retrovir vs. Trizivir

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Works with other drugs to treat HIV infection or prevents transmission to your baby.

Retrovir (zidovudine) is not the first choice to treat HIV because of its side effects.

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Upsides
  • Retrovir (zidovudine) is safe and effective for children and infants.
  • Retrovir (zidovudine) is available in several single-pill combination tablets so you don't need to take as many pills.
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Downsides
  • Retrovir (zidovudine) can cause serious blood, muscle, and liver problems.
  • Many people experience nausea, vomiting, loss of appetite, and headache when taking Retrovir (zidovudine).
  • Taking Retrovir (zidovudine) can raise your cholesterol and blood sugar levels.
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Used for
  • HIV infection
  • Prevention of mother-to-child HIV transmission
  • HIV Postexposure prophylaxis (PEP)
  • HIV infection
Dosage forms
  • Pill
  • Liquid
  • Pill
Price
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Reviews
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Side effects
12possible side effects
  • Fever
    25%
  • Cough
    15%
  • Skin rashes
    12%
  • Enlarged liver
    11%
  • Enlarged lymph nodes
    9%
  • Nausea and vomiting
    8%
  • Diarrhea
    8%
  • Nasal discharge or congestion
    8%
  • Wheezing
    7%
  • Pain in the ear
    7%
  • Swelling of the mouth
    6%
  • Enlarged spleen
    5%
See more detailed side effects
The Trizivir (Abacavir / Lamivudine / Zidovudine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Blood and bone marrow problems
    • Advanced HIV
    • Anemia
    • Neutropenia
  • Muscle and kidney damage
    • Extended use of Retrovir (zidovudine)
  • Acid build-up in the blood
    • Liver disease
    • Women
    • Obesity
  • Fat redistribution
    • HIV treatment
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
See more detailed risks and warnings
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