Compare Reyataz vs. Aptivus

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Reyataz (atazanavir)

Prescription only

Aptivus (tipranavir)

Prescription only
Treats HIV infection.

Reyataz (atazanavir) works well with other HIV medicines to treat HIV, but it's not a first-line choice due to its side effects, and you must take it with food.

Treats HIV infection.

Aptivus (tipranavir) is not the first-choice treatment for HIV because it can cause more side effects and drug interactions than similar alternatives.

Upsides
  • If first-line choices for HIV medicines are not an option, Reyataz (atazanavir) is a good alternative to consider.
  • Conveniently taken once daily.
  • Available in powder form for mixing if pills are hard to swallow.
  • A safer choice than Prezista (darunavir) or Prezcobix (darunavir/cobicistat) for people with heart problems.
  • Good choice for people with kidney problems.
  • Aptivus (tipranavir) comes in liquid form if you have trouble swallowing pills.
  • Children as young as 2 years old can use Aptivus (tipranavir) safely and effectively.
Downsides
  • Reyataz (atazanavir) can interact with many other medicines. Talk to your doctor or pharmacist before starting or stopping medicines.
  • Not a good choice for people with uncontrolled diabetes, liver problems, or history of gallstones or kidney stones.
  • Needs to be taken with other HIV medicines.
  • Reyataz (atazanavir) powder contains phenylalanine, which is harmful to people who can't digest phenylalanine (i.e., phenylketonuria).
  • Aptivus (tipranavir) can cause high cholesterol and high blood sugars.
  • Aptivus (tipranavir) isn't a good option if you have a sulfa allergy.
  • Use barrier contraceptives, like condoms, when taking Aptivus (tipranavir) because it can make birth control pills less effective.
  • Aptivus (tipranavir) should always be taken with Norvir (ritonavir) to be effective.
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Used for
Dosage forms
  • Pill
  • Powder
  • Pill
  • Liquid
Price
Lowest price
$177.65
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Lowest price
$1698.79
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Reviews
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Side effects
13possible side effects
  • Nausea
    14%
  • Yellowing of skin and eyes
    9%
  • Rash
    7%
  • Headache
    6%
  • Vomiting
    4%
  • Stomach pain
    4%
  • Burning or tingling in hands, arms, legs, or feet
    4%
  • Muscle pain
    4%
  • Trouble sleeping
    3%
  • Diarrhea
    3%
  • Dizziness
    2%
  • Fever
    2%
  • Depression
    2%
See more detailed side effects
20possible side effects
  • Diarrhea
    15%
  • Nausea
    9%
  • Fever
    8%
  • Vomiting
    6%
  • Fatigue
    6%
  • Headache
    5%
  • Abdominal pain
    4%
  • High triglycerides
    4%
  • Low red blood cells
    3%
  • Decreased weight
    3%
  • High cholesterol
    3%
  • Rash
    3%
  • Low white blood cells
    2%
  • Upper abdominal pain
    2%
  • Elevated liver function tests
    2%
  • Dehydration
    2%
  • Muscle pain
    2%
  • Nerve damage
    2%
  • Insomnia
    2%
  • Shortness of breath
    2%
See more detailed side effects
Risks and risk factors
  • Changes in heartbeat
    • History of heartbeat problems
    • Taking other medicines that can affect your heartbeat
  • High bilirubin levels
  • New or worsening diabetes
    • Diabetes
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medicine
    • Change in HIV therapy
  • Liver damage
    • History of liver damage
    • Hepatitis B or C
  • Severe skin reactions
See more detailed risks and warnings
  • Bleeding in the brain
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Liver damage
    • History of liver damage
    • Hepatitis B or C
  • Rash
  • Sulfa allergy
  • Fat redistribution
    • HIV treatment
See more detailed risks and warnings
Learn more about Reyataz (atazanavir)
Learn more about Aptivus (tipranavir)