Compare Rocaltrol vs. Zemplar

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zemplar (paricalcitol)

Prescription only

Raises Vitamin D levels.

Rocaltrol (Calcitriol) is the strongest form of vitamin D available, but it's prescription-only and more expensive than over-the-counter alternatives, and you have to get regular blood tests.

Treats high parathyroid hormone levels.

Zemplar (paricalcitol) works well to lower parathyroid hormone levels in people with chronic kidney disease and is safe for people with high blood calcium levels, but can be more expensive than alternatives.

Upsides

The strongest form of vitamin D that's available to help keep your calcium levels in line in case your parathyroid or kidneys aren't working like they should.
Available in generic.
Available in both intravenous infusion and oral capsule form.

Works well to lower parathyroid hormone levels.
Less likely to raise your blood calcium and phosphorus levels compared to other medicines in its class.
More convenient dosing than other medicines, like phosphate binders.

Downsides

Your doctor will want to take blood tests to make sure that your body is responding to the medication.
Your doctor may prescribe other medications to make sure other chemicals (phosphate and calcium) in your body remain in balance.
Can interact with antacids containing magnesium.

Because Zemplar (paricalcitol) can affect your blood calcium and phosphorus levels, you may need more blood tests and doctor follow-up visits than alternative medicines.
Both the brand and generic forms of Zemplar (paricalcitol) can be more expensive compared to similar medicines.

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