Compare Rozerem vs. doxepin
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Helps you fall asleep.
Rozerem (ramelteon) is a good sleep medicine that's not addictive, but it can be expensive.
Treats depression and anxiety.
doxepin can treat depression and anxiety, but it's not a first choice medication because of its many side effects.
Upsides
- Rozerem (ramelteon) isn't a controlled medicine, and it's safe to use in people age 65 or older.
- If you stop taking Rozerem (ramelteon) suddenly, your insomnia won't come back.
- Rozerem (ramelteon) won't make you feel hungover or groggy the next day.
- doxepin has been consistently shown to improve symptoms of depression and anxiety.
- doxepin has been used to treat depression for over forty years.
Downsides
- Rozerem (ramelteon) is only available as a brand name.
- Rozerem (ramelteon) is only available in 1 strength.
- If you take Rozerem (ramelteon) on a full stomach, it won't work as well.
- Not recommended for children.
- Rozerem (ramelteon) can't be used if you have sleep apnea.
- doxepin can make you very sleepy. Try taking it at bedtime if you need to be alert during the day.
- You shouldn't drink alcohol with doxepin. It can worsen side effects like drowsiness.
- You have to take it daily, especially if you are feeling better, for the medicine to do its job.
- It can have more side effects than other antidepressants, like weight gain and increased appetite, decreased libido, and sleepiness.
- It's not unusual for people to try different antidepressants until they find one that works for them.
Used for
Dosage forms
- Pill
- Pill
- Liquid
Price
Lowest price
$402.30
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$10.79
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Reviews
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Side effects
5possible side effects
- Dizziness4%
- Sleepiness3%
- Fatigue3%
- Nausea3%
- Worsening insomnia3%
The doxepin FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Severe allergic reaction
- Behavior changes
- Sleepiness
- Breathing problems
- Alcohol
- Taking narcotics, tranquilizers, or antihistamines
- Hormonal changes
- Suicidal thoughts or behavior
- Age 24 years or under
- Unmasking of bipolar disorder
- Bipolar disorder
- Serotonin syndrome
- Taking MAOIs (monoamine oxidase inhibitors)
- Heart problems
- History of heart disease
- Adults over 65
- Electrolyte imbalance
- Sleepiness
- Adults 65 years or older
- Taking other medicines that cause drowsiness (antihistamines, sleep medications, narcotic pain medications)
- Alcohol
- Dizziness and falls
- Age 65 years or older