Compare Rozerem vs. Unisom

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Rozerem (ramelteon)

Prescription only

Unisom Sleeptabs (Doxylamine)

Prescription or OTC
Helps you fall asleep.

Rozerem (ramelteon) is a good sleep medicine that's not addictive, but it can be expensive.

Treats allergy symptoms and helps you sleep.

Unisom Sleeptabs (Doxylamine) can help you get a good night's sleep, but you can have a hard time waking up if you don't give yourself enough time to sleep.

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3.3/ 5 average rating with 585 reviewsforUnisom
Upsides
  • Rozerem (ramelteon) isn't a controlled medicine, and it's safe to use in people age 65 or older.
  • If you stop taking Rozerem (ramelteon) suddenly, your insomnia won't come back.
  • Rozerem (ramelteon) won't make you feel hungover or groggy the next day.
  • Works well to help you fall asleep and doesn't make you feel groggy the next morning.
  • Has fewer side effects than prescription sleep aid medications.
  • Available over the counter without a prescription.
  • Not habit-forming like other sleep aids can be.
Downsides
  • Rozerem (ramelteon) is only available as a brand name.
  • Rozerem (ramelteon) is only available in 1 strength.
  • If you take Rozerem (ramelteon) on a full stomach, it won't work as well.
  • Not recommended for children.
  • Rozerem (ramelteon) can't be used if you have sleep apnea.
  • Shouldn't be used unless you have a full night to sleep.
  • You shouldn't drive after taking Unisom Sleeptabs (Doxylamine) until you know how it affects you.
  • Drinking alcohol while taking Unisom Sleeptabs (Doxylamine) isn't recommended.
  • It can increase the risk of falls, so elderly people shouldn't use Unisom Sleeptabs (Doxylamine).
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Used for
Dosage forms
  • Pill
  • Pill
  • Chewable tablet
  • Liquid
Price
Lowest price
$386.24
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Lowest price
$4.86
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Reviews
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585 reviews so far
58%
saidit'sworth it
32%
saiditworked well
11%
saidit'sa big hassle

Have you used Unisom Sleeptabs (Doxylamine)?

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Side effects
5possible side effects
  • Dizziness
    4%
  • Sleepiness
    3%
  • Fatigue
    3%
  • Nausea
    3%
  • Worsening insomnia
    3%
See more detailed side effects
The Unisom Sleeptabs (Doxylamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Severe allergic reaction
  • Behavior changes
  • Sleepiness
  • Breathing problems
    • Alcohol
    • Taking narcotics, tranquilizers, or antihistamines
  • Hormonal changes
See more detailed risks and warnings
  • Overdosage
    • Using other drugs with similar ingredients
  • Increased side effects
    • Age 65 years or older
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Hyperactivity
    • Children age 6 years or younger
  • Trouble urinating
    • Enlarged prostate
    • History of bladder problems
  • Vision changes
    • Glaucoma
  • Breastfeeding
    • Nursing mothers
See more detailed risks and warnings
Learn more about Rozerem (ramelteon)
Learn more about Unisom Sleeptabs (Doxylamine)