Compare Savaysa vs. Eliquis

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Savaysa (edoxaban)

Prescription only

Eliquis (apixaban)

Prescription only
Prevents blood clots.

Savaysa (edoxaban) can prevent blood clots without food restrictions or frequent blood tests. However, its effects will be hard to reverse in the event of an overdose.

Prevents blood clots.

Eliquis (apixaban) is an effective way to prevent blood clots from forming in your veins, but you have to take it twice a day, and your doctor might have to change the dose a lot.

3.8/ 5 average rating with 19 reviewsforEliquis
  • Works as well as other blood thinners to prevent strokes or blood clots.
  • Does not require frequent blood tests like warfarin.
  • Does not require food restrictions like warfarin.
  • Eliquis (apixaban) is very effective in reducing the risk of stroke in people with atrial fibrilation or other clotting disorders.
  • You don't need to have regular blood tests on Eliquis (apixaban), and you don't have to regulate your diet like other blood thinners.
  • If you've had clots in your legs or lungs before, Eliquis (apixaban) can lower the risk of these forming again.
  • Taking Savaysa (edoxaban) raises your risk of bleeding and bruising. If you take Savaysa (edoxaban) along with other anti-inflammatory medicines like aspirin or ibuprofen, this can make you even more likely to bleed and bruise easily.
  • Savaysa (edoxaban) is not available as a generic medicine so it can be quite pricey.
  • You may not be able to concentrate enough drug in your blood if your kidney works really well. Your doctor should check your kidney function before starting treatment.
  • Savaysa (edoxaban) cannot be used in people with mechanical heart valves or valvular atrial fibrillation.
  • There is no antidote for Savaysa (edoxaban).
  • You can bruise easier and if you cut yourself, it'll take longer to stop the bleeding. Always look for signs of internal bleeding, such as dark urine or bloody stools.
  • Can't be used if you have artificial heart valves.
  • Never stop taking Eliquis (apixaban) without talking to your doctor first.
  • Eliquis (apixaban) isn't available as a generic, so it can be expensive.
  • If you've taken too much Eliquis (apixaban) and you're bleeding, it can be harder to treat compared to other blood thinners.
Used for
  • Prevention of stroke and blood clots in nonvalvular atrial fibrillation
  • Treatment of major blood clots (deep vein thrombosis and pulmonary embolism)
Dosage forms
  • Pill
  • Pill
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19 reviews so far
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Side effects
2possible side effects
  • Major bleeding
  • Bleeding of the stomach
See more detailed side effects
1possible side effects
  • Major bleed
See more detailed side effects
Risks and risk factors
  • Not enough medicine in your blood
    • Excellent kidney function (filtration rate more than 95 mL/min
  • Blood clots and stroke
    • Stopping Savaysa (edoxaban) too early
    • Mechanical heart valve
    • Narrow mitral valve in the heart
  • Blood clot in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
  • Unusual bleeding
    • History of bleeding problems
    • Severe high blood pressure
    • Age 65 or older
    • Taking anti-inflammatory medicines like aspirin and ibuprofen
    • Taking other blood-thinning medicines
  • Increased side effects
    • Current kidney problems
    • Current liver problems
See more detailed risks and warnings
  • Increased risk of stroke or blood clots from early discontinuation
    • Stopping Eliquis (apixaban) prematurely
  • Paralysis in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
    • History of spinal surgery
    • Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs), or other blood-thinners
  • Interactions with other drugs
  • Increased risk of stroke or bleeding
    • Artificial heart valve
  • Increased side effects in kidney or liver conditions
    • Current kidney problems
    • Current liver problems
See more detailed risks and warnings