Compare Saxenda vs. phentermine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Saxenda (liraglutide)

Prescription only

Adipex-P (phentermine)

Prescription only
Helps you lose weight.

Saxenda (liraglutide) helps to jump start weight loss in combination with diet and exercise, but may be expensive.

Helps you lose weight.

Adipex-P (phentermine) is not a first choice medicine for weight loss because it is associated with an increased risk for side effects and abuse potential. However, it can be used as a short-term treatment option if other similar medicines don't work.

3.1/ 5 average rating with 40 reviewsforphentermine
Upsides
  • Can help lose up to 8% in body weight when combined with diet and exercise.
  • Saxenda (liraglutide) is ideal for patients with diabetes because it can also lower blood sugar levels.
  • Adipex-P (phentermine) is effective at lowering appetite and helping with weight loss.
  • Available in generic form, which is more affordable.
  • You only need to take it for a short period of time.
Downsides
  • Must be given by injection.
  • Expensive if not covered by your insurance.
  • Won't keep weight off in the long run, especially if not used in combination with diet and exercise.
  • Most insurance companies don't cover the cost of Adipex-P (phentermine), so you may have to pay out-of-pocket for it.
  • Adipex-P (phentermine) is only safe to be used for up to 12 weeks at a time and isn't for long-term treatment.
  • Adipex-P (phentermine) can be habit-forming and addictive so your doctor will have you use the lowest dose possible.
  • Not appropriate for people with high blood pressure and hyperthyroidism.
  • People age 65 or older are at a higher risk for experiencing side effects while using Adipex-P (phentermine).
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Used for
  • Obesity (short-term add-on treatment)
Dosage forms
  • Injection
  • Pill
Price
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Reviews
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40 reviews so far
53%
saidit'sworth it
43%
saiditworked well
18%
saidit'sa big hassle

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Side effects
24possible side effects
  • Nausea
    39%
  • Low blood sugar levels
    23%
  • Diarrhea
    21%
  • Constipation
    19%
  • Vomiting
    16%
  • Headache
    14%
  • Indigestion
    10%
  • Decreased appetite
    10%
  • Fatigue
    8%
  • Dizziness
    7%
  • Abdominal pain
    5%
  • Upper abdominal pain
    5%
  • Acid reflux
    5%
  • Bloating
    5%
  • Belching
    5%
  • Stomach flu
    5%
  • High blood lipase levels
    5%
  • Gas
    4%
  • Urinary tract infection
    4%
  • Injection site reaction
    3%
  • Dry mouth
    2%
  • Lack of energy
    2%
  • Insomnia
    2%
  • Anxiety
    2%
See more detailed side effects
The Adipex-P (phentermine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Thyroid cancer
    • History of MTC
    • History of MEN 2
  • Inflammation of the pancreas (pancreatitis)
    • History of pancreatitis
    • History of gallstones
    • alcoholism
    • Elevated triglycerides
  • Unexplained changes in mood
    • History of depression
  • Kidney damage
    • Kidney problems
    • dehydration
  • Low blood sugar
    • Use of insulin(s)
    • Use of insulin-secreting medicines.
  • Stomach upset
    • Stomach or digestive tract disease
    • Gastroparesis
See more detailed risks and warnings
  • High blood pressure in the lungs
  • Potential for tolerance and abuse
    • Using Adipex-P (phentermine) for a long period of time
    • History of drug abuse
  • Worsening of heart disease
    • History of heart problems
  • Effect on blood pressure
    • History of high blood pressure
  • Using other weight loss medicines
    • Taking other weight loss medicines
See more detailed risks and warnings