Compare scopolamine vs. Aloxi

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Aloxi (palonosetron)

Prescription only
Prevents nausea and vomiting.

Transderm-Scop (scopolamine) is a low-hassle patch that works well to prevent nausea and vomiting, but it takes several hours to work.

3.9/ 5 average rating with 26 reviewsforscopolamine
Stops nausea caused by chemotherapy or surgery.

Aloxi (palonosetron) is given one time to effectively reduce nausea from chemotherapy or surgery. In some cases, it will only help for a short period of time.

Upsides
  • Transderm-Scop (scopolamine) is well tolerated.
  • Prevents nausea for 3 days.
  • Because Transderm-Scop (scopolamine) is a skin patch, it's a good alternative to stopping nausea and vomiting if you're not able to swallow pills.
  • Aloxi (palonosetron) can be given through the same IV line as your chemotherapy - as a one-time dose 30 minutes before treatment starts.
  • Starts working in 30 minutes.
  • Aloxi (palonosetron) can be used in children as young as 1 month of age.
Downsides
  • Can only be used for prevention of nausea and vomiting. It can't stop nausea or vomiting that's already happening.
  • The side effects can be worse if you are 65 and older.
  • You might feel sleepy, drowsy, or have blurry vision while taking Transderm-Scop (scopolamine). Taking alcohol or other medicines that make you drowsy can make this effect worse.
  • You're more likely to have heat stroke or feel dehydrated.
  • It takes a few hours for Transderm-Scop (scopolamine) to kick in, so you have to remember to take it beforehand.
  • If your chemotherapy is very likely to make you feel queasy or if you have nausea after surgery, Aloxi (palonosetron) is usually only helpful for one day.
  • Can only be used to prevent nausea and vomiting, not to treat if it's already happening.
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Used for
  • Nausea and vomiting from chemotherapy or surgery
Dosage forms
  • Patch
  • Injection
Price
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Reviews
26 reviews so far
73%
saidit'sworth it
58%
saiditworked well
19%
saidit'sa big hassle

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Side effects
The Transderm-Scop (scopolamine) FDA package insert doesn’t have numbers about how common side effects are.
4possible side effects
  • Abnormal heartbeat
    5%
  • Slow heart rate
    4%
  • Headache
    3%
  • Constipation
    2%
See more detailed side effects
Risks and risk factors
  • Increased pressure in the eyes
    • Open angle glaucoma
  • Worsening stomach, bowel, or bladder blockages
    • Blockages in the stomach, bowels or bladder
  • Skin burns
    • MRI examination
  • Heat stroke
  • Worsening seizures or psychosis
    • History of seizures
    • History of psychosis
  • Sleepiness and dizziness
    • Taking with alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings
  • Serotonin syndrome
    • Taking antidepressants, lithium, some migraine medications, and St. John's wort.
  • Severe allergic reaction
See more detailed risks and warnings