Compare simvastatin vs. Antara

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Zocor (simvastatin)

Prescription only

Antara (fenofibrate)

Prescription only
Lowers cholesterol.

Zocor (simvastatin) is a good medication to improve your cholesterol.

3.8/ 5 average rating with 1176 reviewsforsimvastatin
Lowers cholesterol and triglycerides.

Antara (fenofibrate) is effective at lowering triglyceride and cholesterol levels, but may cause liver problems and muscle pain.

2.5/ 5 average rating with 56 reviewsforAntara
Upsides
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Available in generic.
  • Available in combination pills with other cholesterol medicines.
  • Antara (fenofibrate) can reduce triglycerides by about 20-50%.
  • Although not as effective at lowering triglycerides, Antara (fenofibrate) can lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
  • There is a less expensive generic version available.
  • You only need to take it once a day, with or without food.
Downsides
  • You are at higher risk for side effects if you are female, are 65 years or older, drink alcohol every day, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
  • Can have more drug interactions than some other drugs in the same class (statins).
  • Not as effective as statins in lowering cholesterol levels. You shouldn't take Antara (fenofibrate) by itself to lower cholesterol.
  • Drinking large amounts of alcohol regularly while taking Antara (fenofibrate) can increase your risk of liver damage.
  • Tell your doctor if you have a history of gallbladder, liver or kidney disease. Antara (fenofibrate) might not be the best choice to lower your triglyceride levels.
  • Antara (fenofibrate) can interact with other medications such as warfarin, colchicine, and sulfonylureas.
  • Antara (fenofibrate) was not shown to reduce rates of death in people with type 2 diabetes.
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Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
1176 reviews so far
61%
saidit'sworth it
48%
saiditworked well
14%
saidit'sa big hassle

Have you used Zocor (simvastatin)?

Leave a review
56 reviews so far
27%
saidit'sworth it
14%
saiditworked well
29%
saidit'sa big hassle

Have you used Antara (fenofibrate)?

Leave a review
Side effects
14possible side effects
  • Bronchitis
    7%
  • Abdominal pain
    6%
  • Atrial fibrillation
    6%
  • Stomach problems
    5%
  • Balance problems
    5%
  • Eczema
    5%
  • Diabetes
    4%
  • Muscle pain
    4%
  • Insomnia
    4%
  • Edema/swelling
    3%
  • Headache
    3%
  • Infection, urinary tract
    3%
  • Constipation
    2%
  • Sinus infection
    2%
See more detailed side effects
11possible side effects
  • Abnormal liver function tests
    8%
  • Respiratory disorder
    6%
  • Stomach pain
    5%
  • Back pain
    3%
  • Headache
    3%
  • Increased AST
    3%
  • Increased ALT
    3%
  • Increased creatine phosphokinase
    3%
  • Nausea
    2%
  • Constipation
    2%
  • Hay fever
    2%
See more detailed side effects
Risks and risk factors
  • Muscle pain and kidney damage
    • Kidney disease
    • High dose of Zocor (simvastatin)
    • Combining Zocor (simvastatin) with other cholesterol-lowering drugs
    • Older age
    • Female gender
  • Liver damage
    • Heavy alcohol use
    • History of chronic liver disease
  • Harm to unborn baby
    • Pregnancy
    • Breast feeding
  • Drug interactions
    • Certain drugs can increase the dose of Zocor (simvastatin) in the body
  • High blood sugar
    • History of high blood sugar
See more detailed risks and warnings
  • Muscle pain
    • Taking Antara (fenofibrate) with statins
    • Elderly patients
    • Patients with diabetes
    • Patients with a history of renal failure.
  • Liver damage
    • History of liver disease
  • Gallstones
    • History of gallstones
  • Increased bleeding risk
    • Taking Antara (fenofibrate) with anticoagulants
  • Inflammation of pancreas
  • Changes in blood tests
See more detailed risks and warnings