Compare simvastatin vs. Livalo

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Zocor (simvastatin)

Prescription only

Livalo (pitavastatin)

Prescription only
Lowers cholesterol.

Zocor (simvastatin) is a good medication to improve your cholesterol.

3.8/ 5 average rating with 1176 reviewsforsimvastatin
Lowers cholesterol.

Livalo (pitavastatin) lowers your cholesterol and prevents heart disease, but may be more expensive than other medicines that work just like it.

  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Available in generic.
  • Available in combination pills with other cholesterol medicines.
  • Good add-on therapy for reducing cholesterol if diet and exercise aren't enough.
  • Lowers your risk for heart attack, stroke, and death.
  • Livalo (pitavastatin) has fewer drug interactions with HIV medications compared to other cholesterol-lowering treatment options.
  • You are at higher risk for side effects if you are female, are 65 years or older, drink alcohol every day, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
  • Can have more drug interactions than some other drugs in the same class (statins).
  • Expensive if not covered by insurance.
  • Cholesterol-lowering effect may not be enough if you have very high cholesterol.
  • Many cannot tolerate this medicine and ones similar to it, because of severe pains and muscle aches.
Used for
  • High cholesterol and fats in the blood
Dosage forms
  • Pill
  • Pill
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1176 reviews so far
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Side effects
14possible side effects
  • Bronchitis
  • Abdominal pain
  • Atrial fibrillation
  • Stomach problems
  • Balance problems
  • Eczema
  • Diabetes
  • Muscle pain
  • Insomnia
  • Edema/swelling
  • Headache
  • Infection, urinary tract
  • Constipation
  • Sinus infection
See more detailed side effects
The Livalo (pitavastatin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Muscle pain and kidney damage
    • Kidney disease
    • High dose of Zocor (simvastatin)
    • Combining Zocor (simvastatin) with other cholesterol-lowering drugs
    • Older age
    • Female gender
  • Liver damage
    • Heavy alcohol use
    • History of chronic liver disease
  • Harm to unborn baby
    • Pregnancy
    • Breast feeding
  • Drug interactions
    • Certain drugs can increase the dose of Zocor (simvastatin) in the body
  • High blood sugar
    • History of high blood sugar
See more detailed risks and warnings
  • High blood sugars
  • Liver damage
    • Heavy alcohol use
    • Prior history of chronic liver disease
  • Muscle pain
    • High doses of Livalo (pitavastatin)
    • Elderly
  • Birth defects
See more detailed risks and warnings