Compare Sirturo vs. Cipro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Sirturo (bedaquiline)

Prescription only

Cipro (ciprofloxacin)

Prescription only
Used to treat active tuberculosis when other medications cannot be used.

Sirturo (bedaquiline) is a great addition to tuberculosis regimens but only if your tuberculosis can't be treated with all of the typical tuberculosis drugs.

Treats bacterial infections.

Cipro (ciprofloxacin) is a good, cheap antibiotic that treats many types of bacterial infections, but it interacts with some food and drugs.

3.8/ 5 average rating with 755 reviewsforCipro
Upsides
  • Sirturo (bedaquiline) is the first drug with a new method of treating multi-drug resistant tuberculosis to be developed in over 40 years.
  • After two weeks of taking Sirturo (bedaquiline) each day, you will only need to take it three times a week for the rest of your therapy.
  • Cipro (ciprofloxacin) is available in generic.
  • Cipro (ciprofloxacin) comes in different forms, including intravenous (IV) injection.
Downsides
  • Sirturo (bedaquiline) should not be taken alone to treat your tuberculosis. You must take it with at least 3 other medications.
  • It is recommended you take Sirturo (bedaquiline) by directly observed therapy or in front of a health worker.
  • Like other tuberculosis drugs, Sirturo (bedaquiline) has to be given for several months in order for it work properly (usually 6 months).
  • A study found an increased risk of death with Sirturo (bedaquiline). You can only take it when the standard tuberculosis treament is not enough to treat you of tuberculosis.
  • Sirturo (bedaquiline) cannot be used for latent (or non-active) tuberculosis or for tuberculosis that has spread outside the lungs.
  • Cipro (ciprofloxacin) should be used with caution if you have kidney problems.
  • If you drink caffeine while on Cipro (ciprofloxacin), you may notice increased effects of the caffeine.
  • Some bacteria have developed resistance to Cipro (ciprofloxacin).
  • Cipro (ciprofloxacin) can interact with many other medications. Tell your doctor and pharmacist what medications, over-the-counter products, and supplements you are taking before starting Cipro (ciprofloxacin).
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Used for
Dosage forms
  • Pill
  • Pill
  • Liquid
  • Injection
  • Extended release pill
Price
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Reviews
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755 reviews so far
63%
saidit'sworth it
53%
saiditworked well
17%
saidit'sa big hassle

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Side effects
9possible side effects
  • Nausea
    38%
  • Joint pain
    33%
  • Headache
    28%
  • Coughing up blood
    18%
  • Chest pain
    11%
  • Loss of appetite
    9%
  • Abnormal liver labs
    9%
  • Rash
    8%
  • Pancreatitis
    3%
See more detailed side effects
2possible side effects
  • Nausea
    3%
  • Diarrhea
    2%
See more detailed side effects
Risks and risk factors
  • Increased risk of death
  • Heart rhythm problems
    • Use with other QT prolonging drugs
    • History of heart disease
  • Liver damage
    • History of liver damage
    • Alcohol intake
    • Use with other drugs that are harmful to the liver
See more detailed risks and warnings
  • Tendon rupture
    • People over age 60
    • Taking steroid medicine
    • Those with kidney, heart, or lung transplants
  • Myasthenia gravis
    • Myasthenia gravis
  • Diarrhea
  • Nerve damage
  • Central nervous system effects
    • Central nervous system disorders
    • Seizures
  • Heart rhythm problems
    • Use with other QT prolonging drugs
    • History of heart disease
See more detailed risks and warnings