Compare Sirturo vs. Mycobutin
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Used to treat active tuberculosis when other medications cannot be used.
Sirturo (bedaquiline) is a great addition to tuberculosis regimens but only if your tuberculosis can't be treated with all of the typical tuberculosis drugs.
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Upsides
- Sirturo (bedaquiline) is the first drug with a new method of treating multi-drug resistant tuberculosis to be developed in over 40 years.
- After two weeks of taking Sirturo (bedaquiline) each day, you will only need to take it three times a week for the rest of your therapy.
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Downsides
- Sirturo (bedaquiline) should not be taken alone to treat your tuberculosis. You must take it with at least 3 other medications.
- It is recommended you take Sirturo (bedaquiline) by directly observed therapy or in front of a health worker.
- Like other tuberculosis drugs, Sirturo (bedaquiline) has to be given for several months in order for it work properly (usually 6 months).
- A study found an increased risk of death with Sirturo (bedaquiline). You can only take it when the standard tuberculosis treament is not enough to treat you of tuberculosis.
- Sirturo (bedaquiline) cannot be used for latent (or non-active) tuberculosis or for tuberculosis that has spread outside the lungs.
No information currently available
Used for
- Pulmonary tuberculosis
- Disseminated infection due to Mycobacterium avium-intracellulare group; Prophylaxis - HIV infection
- Atypical mycobacterial infection Crohn's disease Disseminated infection due to Mycobacterium avium-intracellulare group - HIV infection Helicobacter pylori gastrointestinal tract infection HIV infection - Tuberculosis Mycobacterium avium complex infection
- Lung disease Tuberculosis Tuberculosis
- Extrapulmonary
Dosage forms
- Pill
- Pill
Price
Lowest price
$3809.17
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$107.47
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Side effects
9possible side effects
- Nausea38%
- Joint pain33%
- Headache28%
- Coughing up blood18%
- Chest pain11%
- Loss of appetite9%
- Abnormal liver labs9%
- Rash8%
- Pancreatitis3%
The Mycobutin (Rifabutin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Increased risk of death
- Heart rhythm problems
- Use with other QT prolonging drugs
- History of heart disease
- Liver damage
- History of liver damage
- Alcohol intake
- Use with other drugs that are harmful to the liver
No information currently available