Compare Sivextro vs. daptomycin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Sivextro (tedizolid)

Prescription only

Cubicin (daptomycin)

Prescription only
Treats bacterial infections.

Sivextro (tedizolid) has a more convenient, daily dosing and shorter course of therapy, but is more expensive than other medicines that work just like it.

Treats bacterial infections.

Cubicin (daptomycin) is an antibiotic that's usually only given in the hospital for serious infections. It can be given at home, but you will have to be taught how to inject it correctly.

Upsides
  • Taken once daily.
  • Full course of treatment is shorter compared to other anti-bacterials (6 days vs. 7-14 days).
  • May cause less stomach and bone marrow effects than Zyvox (linezolid)
  • Cubicin (daptomycin) is good at treating severe and complicated bacterial infections.
  • It is able to kill bacteria that have resistance to other antibiotics.
  • Most people who take Cubicin (daptomycin) have few side effects.
  • You usually only need to take it once a day.
Downsides
  • Available as brand version only so can be expensive.
  • Cubicin (daptomycin) is usually only given for extremely serious infections that haven't responded to other antibiotics.
  • Cubicin (daptomycin) can cause muscle aches and weakness, which can lead to kidney problems.
  • You might need to have more blood tests done while taking Cubicin (daptomycin).
  • Like most antibiotics, it is common to have diarrhea when taking this medicine.
  • While Cubicin (daptomycin) is generic, it is usually very expensive.
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Used for
Dosage forms
  • Pill
  • Injection
Price
Lowest price
$2294.86
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Reviews
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Side effects
5possible side effects
  • Nausea
    8%
  • Headache
    6%
  • Diarrhea
    4%
  • Vomiting
    3%
  • Dizziness
    2%
See more detailed side effects
9possible side effects
  • Diarrhea
    5%
  • Headache
    5%
  • Rash
    4%
  • Abnormal liver tests
    3%
  • Muscle damage
    3%
  • Dizziness
    2%
  • Urinary tract infection
    2%
  • Low blood pressure
    2%
  • Shortness of breath
    2%
See more detailed side effects
Risks and risk factors
  • New infection
    • Taking Sivextro (tedizolid) for a long time
  • Development of drug-resistant bacteria
    • Using Sivextro (tedizolid) for a long time
  • Low white blood cells
See more detailed risks and warnings
  • Allergic reaction
    • Allergy to antibiotics
  • Muscle pain & kidney damage
    • History of kidney problems
    • Taking statins to lower cholesterol
  • Pneumonia
    • Taking Cubicin (daptomycin) for at least 2 to 4 weeks
  • Nerve damage
  • Diarrhea
See more detailed risks and warnings