Compare Soma vs. Norflex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Soma (carisoprodol)

Prescription only

Norflex (orphenadrine)

Prescription only
Relaxes your muscles.

Soma (carisoprodol) is used for muscle spasms and muscle pain but it's not considered a first-choice treatment and not meant for long-term therapy.

3.5/ 5 average rating with 220 reviewsforSoma
Relaxes your muscles.

Norflex (orphenadrine) can be used for relaxing muscle spasms and it also can relieve pain.

Upsides
  • Patients treated with Soma (carisoprodol) experienced improvement in function.
  • Available in generic.
  • Available in two different strengths.
  • More effective than placebo for treatment of muscle spasms and nonspecific musculoskeletal pain in the short term.
  • Extended release pills last 12 hours.
  • Available as generic.
Downsides
  • Not first choice for treating muscle spasms or muscle pain, because it can cause dependence.
  • Can cause dizziness and sleepiness.
  • Not meant for long-term therapy, because it hasn't been shown to be effective after taking it for a short period.
  • Can cause withdrawal symptoms if you stop taking it suddenly.
  • Not a first choice treatment for muscle spasms.
  • Norflex (orphenadrine) can make you sleepy or drowsy.
  • At higher doses, Norflex (orphenadrine) can make you confused or hallucinate.
  • Dry mouth and difficulty urinating can happen at higher doses.
  • Pills cannot be crushed and must be swallowed whole.
  • Can't be used in people with glaucoma, certain types of bowel obstruction or peptic ulcers, prostatic hypertrophy, certain urinary problems, cardio-spasm (megaesophagus) and myasthenia gravis.
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Used for
Dosage forms
  • Pill
  • Extended release pill
  • Pill
  • Injection
Price
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Reviews
220 reviews so far
61%
saidit'sworth it
39%
saiditworked well
9%
saidit'sa big hassle

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Side effects
3possible side effects
  • Drowsiness
    13%
  • Dizziness
    8%
  • Headache
    5%
See more detailed side effects
The Norflex (orphenadrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Sleepiness and dizziness
    • Taking other medications that also cause sleepiness
    • Recreational drug use
    • Excessive alcohol use
    • Elderly
  • Abuse, dependence and withdrawal
    • Prior history of drug abuse
    • Taking Soma (carisoprodol) for a long time
  • Seizures
    • Prior history of overdoses of drugs of abuse, recreational drugs, or alcohol
See more detailed risks and warnings
  • Sleepiness and dizziness
    • Taking other medications that also cause sleepiness
    • Recreational drug use
    • Excessive alcohol use
  • Abuse, dependence and withdrawal
    • Prior history of drug abuse
  • Heart problems
    • History of fast or irregular heartbeat
    • History of heart failure or other heart problems
See more detailed risks and warnings