Compare Spectracef vs. Keflex

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Spectracef (cefditoren)

Prescription only

Keflex (cephalexin)

Prescription only
Treats bacterial infections.

Spectracef (cefditoren) is good for treating many bacterial infections and it works best if you take the full course without stopping.

Treats bacterial infections.

Keflex (cephalexin) is good for treating many bacterial infections, and is available as a generic.

3.7/ 5 average rating with 686 reviewsforKeflex
  • Spectracef (cefditoren) can be taken with birth control pills.
  • People usually have few side effects when taking Spectracef (cefditoren).
  • Spectracef (cefditoren) is available as a generic.
  • Available in generic.
  • Available in different forms: tablet, capsule, and suspension.
  • Used to treat many types of bacterial infections.
  • Can be taken with or without food.
  • Generally few side effects compared with other antibiotics.
  • Spectracef (cefditoren) can interact with blood thinners and make you more likely to bleed.
  • You can't take Spectracef (cefditoren) and antacids at the same time. Your pharmacist can help you figure out when the best time to take your antacids is.
  • If you're diabetic, Spectracef (cefditoren) can cause a false positive result if you're using Clinitest to measure your urine sugar levels. Talk to your doctor about alternative urine sugar tests.
  • Spectracef (cefditoren) can also affect other lab test so let your physicians know that you're taking Spectracef (cefditoren).
  • Can cause diarrhea.
  • You may need to take Keflex (cephalexin) 2 to 4 times a day, which can be hard to remember.
  • If you're allergic to penicillins or other antibiotics, you might not be able to take this medicine.
Used for
Dosage forms
  • Pill
  • Pill
  • Liquid
No pricing information available
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686 reviews so far
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Side effects
The Spectracef (cefditoren) FDA package insert doesn’t have numbers about how common side effects are.
The Keflex (cephalexin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Risk of bleeding
    • Poor nutritional state
    • Prolonged treatment
    • Liver disease
    • Kidney disease
    • Anticoagulant therapy
  • Penicillin allergy
    • History of penicillin allergy
  • New infection
    • Taking Spectracef (cefditoren) for a long time
  • Milk protein allergy
  • Low carnitine levels
    • Carnitine deficiency
    • Kidney damage
    • Kidney disease
    • Low muscle mass
  • Diarrhea
See more detailed risks and warnings
  • Diarrhea
  • New infections while taking Keflex (cephalexin)
    • Weakened immune system
    • Not taking Keflex (cephalexin) correctly
  • Allergic reaction
    • History of penicillin or cephalosporin allergies
See more detailed risks and warnings