Compare Spiriva vs. Xopenex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Spiriva (Tiotropium)

Prescription only

Xopenex (levalbuterol)

Prescription only
Makes it easier to breathe.

Spiriva (Tiotropium) works well to reduce COPD symptoms and flare-ups with fewer side effects than some medicines that open airways, but you have to use it every day.

3.5/ 5 average rating with 74 reviewsforSpiriva
Makes it easier to breathe if you have asthma, bronchitis, or emphysema.

Xopenex (levalbuterol) inhaler is very effective at relieving acute asthma attakcs in more moderate to severe airway conditions, but is more expensive.

Upsides
  • Helps you breathe easier and lessens the need for a fast-acting (rescue) inhaler.
  • Reduces flare-ups and hospitalizations with fewer side effects compared to some other medicines that open airways.
  • You only need to take it once a day.
  • Xopenex (levalbuterol) works within minutes to help you breathe easier when you have breathing difficulty or an attack, especially in more severe conditions.
  • The inhaler can be used in children as young as 4 years old while the nebulizer solution can be used in children 6 years and older.
  • Xopenex (levalbuterol) may have less side effects such as rapid heartbeat than albuterol.
  • It is available as a generic.
  • The nebulizer solution is a good option for children and adults who have difficulty using a handheld inhaler.
Downsides
  • Won't cure your COPD (but it will relieve your symptoms).
  • You'll need to use this medicine for a long time, and you have to take it every day.
  • Can make symptoms of enlarged prostate or urinary blockage worse.
  • Can worsen a certain type of glaucoma.
  • You might feel dizzy or have blurry vision while taking this medicine.
  • Xopenex (levalbuterol) is only relieves immediate symptoms and doesn't work to prevent future attacks, unlike maintenance medicines.
  • May not be the best option if you have a history of seizures, heart problems, thyroid problems or diabetes.
  • Xopenex (levalbuterol) is similar to albuterol, but it can be more expensive, especially the nebulizer solution.
  • Children might find the inhaler and nebulizer difficult to use. Parents or adults may need to help children use this medicine.
  • Unlike albuterol, Xopenex (levalbuterol) nebulizer solution cannot be mixed with other nebulized medicines.
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Used for
Dosage forms
  • Inhaler
  • Inhaler
  • Nebulizer solution
Price
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Reviews
74 reviews so far
64%
saidit'sworth it
46%
saiditworked well
8%
saidit'sa big hassle

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Side effects
36possible side effects
  • Respiratory tract Infection
    41%
  • Dry mouth
    16%
  • Pharyngitis
    13%
  • Sinusitis
    11%
  • Chest pain (non-specific)
    7%
  • Urinary tract Infection
    7%
  • Dyspepsia
    6%
  • Rhinitis
    6%
  • Headache
    6%
  • Edema, Dependent
    5%
  • Abdominal pain
    5%
  • Constipation
    5%
  • Dry Mouth
    5%
  • Vomiting
    4%
  • Myalgia
    4%
  • Infection
    4%
  • Moniliasis
    4%
  • Epistaxis
    4%
  • Rash
    4%
  • Depression
    4%
  • Insomnia
    4%
  • Arthralgia
    4%
  • Allergic reaction
    3%
  • Leg pain
    3%
  • Dysphonia
    3%
  • Parathesia
    3%
  • Gastroinestinal disorder not otherwise specified
    3%
  • Castroesophegeal reflux
    3%
  • Stomatitis
    3%
  • Hypercholesterolemia
    3%
  • Hyperglycemia
    3%
  • Skeletal pain
    3%
  • Angina pectoris
    3%
  • Herpes zoster
    3%
  • Laryngitis
    3%
  • Cataract
    3%
See more detailed side effects
7possible side effects
  • Vomiting
    11%
  • Asthma symptoms
    9%
  • Accidental injury
    9%
  • Sore throat
    8%
  • Stuffy nose
    7%
  • Dizziness
    3%
  • Bronchitis
    3%
See more detailed side effects
Risks and risk factors
  • Serious allergic reaction
    • History of atropine allergic reaction
  • Sudden onset difficulty breathing (paradoxical bronchospasm)
  • Worsening glaucoma
    • History of narrow-angle glaucoma
  • Difficulty urinating
    • History of urinary bladder blockage (urinary obstruction)
    • History of enlarged prostate
  • Serious allergic reaction
    • Severe milk protein allergy
  • Reduced kidney function
    • History of moderate to severe kidney disease
  • Feeling dizzy
    • Taking with other anticholinergic medications
See more detailed risks and warnings
  • Sudden lung spasms
    • First use of a new vial
  • Heart problems
    • History of heart problems
    • High blood pressure
  • Increased side effects
  • Worsening of asthma
  • Allergic reactions
  • Low potassium levels
    • Medicines that lower potassium levels
    • Taking certain diuretics
See more detailed risks and warnings