Compare Starlix vs. glyburide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Starlix (nateglinide)

Prescription only

Diabeta (glyburide)

Prescription only
Lowers blood sugar.

Starlix (nateglinide) can quickly lower your blood sugar, but needs to be timed with your meals.

Lowers blood sugar.

Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.

3.3/ 5 average rating with 110 reviewsforglyburide
Upsides
  • Can quickly lower blood sugar.
  • Good alternative if you have poor kidney function.
  • Can be safely used in people 65 and older.
  • Widely available in generic (cheaper) form.
  • Available as an oral tablet.
  • Lowers your A1c (average blood sugar over time) up to 2%.
  • Available in generic version.
  • Available in single pill combination with other anti-diabetic medicines.
Downsides
  • Take during mealtime.
  • May need to take as often as three times daily.
  • Can easily cause hypoglycemia (low blood sugar) if you don't maintain a consistent diet or exercise schedule.
  • More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
  • You will have to check your blood sugar often when you first start taking it.
  • Can cause weight gain (about 2 to 3 pounds).
  • Not ideal for elderly or those with poor kidney function.
  • May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
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Used for
Dosage forms
  • Pill
  • Pill
Price
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Reviews
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110 reviews so far
45%
saidit'sworth it
34%
saiditworked well
21%
saidit'sa big hassle

Have you used Diabeta (glyburide)?

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Side effects
10possible side effects
  • Common cold
    11%
  • Back pain
    4%
  • Flu symptoms
    4%
  • Dizziness
    4%
  • Joint problems
    3%
  • Diarrhea
    3%
  • Accidental trauma
    3%
  • Inflammation of the airways
    3%
  • Coughing
    2%
  • Low blood sugar
    2%
See more detailed side effects
2possible side effects
  • Nausea and heartburn
    2%
  • Skin allergies
    2%
See more detailed side effects
Risks and risk factors
  • Low blood sugar (hypoglycemia)
    • Changes in meal pattern
    • Changes in how much exercise you do
    • Taking other antidiabetic medications
    • Bad liver or renal function
See more detailed risks and warnings
  • Low blood sugar
    • Over age 65
    • Kidney problems
    • Use of other blood sugar lowering medicines
    • Alcohol
    • Intense physical activity
  • Severe allergic reactions
    • History of sulfa allergies
See more detailed risks and warnings