Compare Strattera vs. Adderall

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Helps you focus and stay alert.

Strattera (atomoxetine) is a choice medication for children and adults with attention-deficit/hyperactivity disorder (ADHD) who cannot take amphetamine-based medications, but has a risk of suicidal thoughts.

3.2/ 5 average rating with 94 reviewsforStrattera
Helps you focus and stay alert.

Adderall (dextroamphetamine / amphetamine) is a first-choice treatment for ADHD that's available as a generic, but it's a stimulant that can cause difficulty sleeping and other side effects.

3.9/ 5 average rating with 1309 reviewsforAdderall
Upsides
  • Strattera (atomoxetine) is one of the few medications used to treat Attention-deficit/hyperactivity disorder that's not a stimulant.
  • It's not a controlled substance compared to other medications used for this condition.
  • Strattera (atomoxetine) is used in combination with counseling or other non-drug therapies to treat ADHD.
  • Strattera (atomoxetine) usually only has to be taken once daily.
  • It is available as a cheaper, generic form.
  • Strattera (atomoxetine) doesn't have to be tapered when discontinued.
  • First-choice medication to treat ADHD.
  • Adderall (dextroamphetamine / amphetamine) is used together with counseling or other non-drug therapies to treat ADHD.
  • Available as an affordable generic medication.
  • Available in both immediate and extended release forms.
  • For the extended release capsule, if you can't swallow the whole capsule, the capsule can be opened, mixed in a spoonful of applesauce, and swallowed.
Downsides
  • Strattera (atomoxetine) is a second-line medication used to treat ADHD. Other medications are usually tried first.
  • Strattera (atomoxetine) can cause liver toxicity. If this occurs, it is likely to happen within the first 120 days of starting treatment.
  • Strattera (atomoxetine) can cause changes in mood and behavior that may lead to suicidal thoughts, unlike alternative ADHD medications.
  • Must take in the morning and early afternoon, otherwise it can cause difficulty sleeping.
  • It's a controlled medication and should be locked up to prevent potential abuse.
  • Not safe for people with a history of heart problems.
  • For school-aged children, a second dose will likely need to be given at school.
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Used for
Dosage forms
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Price
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Reviews
94 reviews so far
46%
saidit'sworth it
32%
saiditworked well
24%
saidit'sa big hassle

Have you used Strattera (atomoxetine)?

Leave a review
1309 reviews so far
74%
saidit'sworth it
53%
saiditworked well
16%
saidit'sa big hassle

Have you used Adderall (dextroamphetamine / amphetamine)?

Leave a review
Side effects
28possible side effects
  • Nausea
    26%
  • Dry mouth
    20%
  • Decreased appetite
    16%
  • Difficulty sleeping
    15%
  • Fatigue
    10%
  • Constipation
    8%
  • Dizziness
    8%
  • Drowsiness
    8%
  • Erectile dysfunction
    8%
  • Stomach pain
    7%
  • Urinary hesitation
    6%
  • Irritability
    5%
  • Indigestion
    4%
  • Vomiting
    4%
  • Abnormal dreams
    4%
  • Ejaculation delayed and/or ejaculation disorder
    4%
  • Sweating
    4%
  • Palpitations
    3%
  • Chills
    3%
  • Burning/prickling sensation
    3%
  • Decreased sex drive
    3%
  • Sleep disorder
    3%
  • Pain during menstruation
    3%
  • Hot flush
    3%
  • Feeling jittery
    2%
  • Thirst
    2%
  • Weight loss
    2%
  • Pain on urination
    2%
See more detailed side effects
The Adderall (dextroamphetamine / amphetamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Suicidal thinking
  • Liver toxicity
  • Serious or life-threatening events
    • History of heart problems
  • Aggressive behavior and mood changes
    • History of psychotic episodes
    • History of Bipolar Disorder
  • Prolonged erection
  • Long-term growth suppression
    • Use of Strattera (atomoxetine) in children
See more detailed risks and warnings
  • Serious or life-threatening cardiovascular events
    • History of heart problems
    • Misuse of Adderall (dextroamphetamine / amphetamine)
  • Dependence and abuse
    • History of drug abuse
    • Misuse of Adderall (dextroamphetamine / amphetamine)
  • Serotonin syndrome
    • Taking other medicines that affect serotonin levels
  • Aggressive behavior and psychosis
    • History of psychotic episodes
    • History of bipolar disorder
  • Driving impairment
    • Taking Adderall (dextroamphetamine / amphetamine) with alcohol
    • Taking other medicines that cause dizziness and/or drowsiness
  • Long-term growth suppression
    • Children ages 7 to 10
See more detailed risks and warnings