Compare Strattera vs. Provigil
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Helps you focus and stay alert.
Strattera (atomoxetine) is a choice medication for children and adults with attention-deficit/hyperactivity disorder (ADHD) who cannot take amphetamine-based medications, but has a risk of suicidal thoughts.
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3.2/ 5 average rating with 94 reviewsforStrattera
Improves alertness.
Provigil (modafinil) is effective in improving alertness, but it interacts with some medicines and shouldn't be used long-term.
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4.2/ 5 average rating with 28 reviewsforProvigil
Upsides
- Strattera (atomoxetine) is one of the few medications used to treat Attention-deficit/hyperactivity disorder that's not a stimulant.
- It's not a controlled substance compared to other medications used for this condition.
- Strattera (atomoxetine) is used in combination with counseling or other non-drug therapies to treat ADHD.
- Strattera (atomoxetine) usually only has to be taken once daily.
- It is available as a cheaper, generic form.
- Strattera (atomoxetine) doesn't have to be tapered when discontinued.
- Provigil (modafinil) is a nonstimulant medication that improves alertness.
- Provigil (modafinil) is available in a cheaper, generic version.
- Provigil (modafinil) is good at decreasing excessive sleepiness in shift work sleep disorder.
- If you need to sleep in the daytime, this medication won't effect you.
Downsides
- Strattera (atomoxetine) is a second-line medication used to treat ADHD. Other medications are usually tried first.
- Strattera (atomoxetine) can cause liver toxicity. If this occurs, it is likely to happen within the first 120 days of starting treatment.
- Strattera (atomoxetine) can cause changes in mood and behavior that may lead to suicidal thoughts, unlike alternative ADHD medications.
- Provigil (modafinil) can be habit forming, so it shouldn't be used for long-term treatment.
- Provigil (modafinil) is not a good choice if you have liver problems.
- May not be a good option if you are taking hormonal contraception like birth control pills.
Used for
- Narcolepsy
- Sleep apnea
- Shift work sleep disorder
- Attention Deficit Hyperactivity Disorder (ADHD)
- Major depressive disorder
- Multiple sclerosis-related fatigue
Dosage forms
- Pill
- Pill
Price
Lowest price
$30.48
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$28.60
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Reviews
94 reviews so far
46%
saidit'sworth it
32%
saiditworked well
24%
saidit'sa big hassle
Have you used Strattera (atomoxetine)?
Leave a review28 reviews so far
82%
saidit'sworth it
71%
saiditworked well
4%
saidit'sa big hassle
Have you used Provigil (modafinil)?
Leave a reviewSide effects
28possible side effects
- Nausea26%
- Dry mouth20%
- Decreased appetite16%
- Difficulty sleeping15%
- Fatigue10%
- Constipation8%
- Dizziness8%
- Drowsiness8%
- Erectile dysfunction8%
- Stomach pain7%
- Urinary hesitation6%
- Irritability5%
- Indigestion4%
- Vomiting4%
- Abnormal dreams4%
- Ejaculation delayed and/or ejaculation disorder4%
- Sweating4%
- Palpitations3%
- Chills3%
- Burning/prickling sensation3%
- Decreased sex drive3%
- Sleep disorder3%
- Pain during menstruation3%
- Hot flush3%
- Feeling jittery2%
- Thirst2%
- Weight loss2%
- Pain on urination2%
25possible side effects
- Headache34%
- Nausea11%
- Nervousness7%
- Stuffy nose7%
- Back pain6%
- Diarrhea6%
- Indigestion5%
- Difficulty sleeping5%
- Anxiety5%
- Dizziness5%
- Flu symptoms4%
- Dry mouth4%
- Loss of appetite4%
- Throat inflammation4%
- Chest pain3%
- High blood pressure3%
- Fast heart beat2%
- Palpitation2%
- Dilation of blood vessels2%
- Constipation2%
- Abnormal liver function2%
- Depression2%
- Burning/tingling sensation2%
- Drowsiness2%
- Lung disorder2%
Risks and risk factors
- Suicidal thinking
- Liver toxicity
- Serious or life-threatening events
- History of heart problems
- Aggressive behavior and mood changes
- History of psychotic episodes
- History of Bipolar Disorder
- Prolonged erection
- Long-term growth suppression
- Use of Strattera (atomoxetine) in children
- Serious allergic reactions
- Allergy to Provigil (modafinil)
- Heart problems
- History of heart problems
- Increased side effects
- Current kidney problems
- Current liver problems
- Driving impairment
- Taking with alcohol or drugs