Compare Stribild vs. Sustiva
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats HIV infection.
Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir) is a convenient 4-in-1 medication and one of the first choices used to treat HIV infections.
Works with other medicines to treat HIV infection.
Sustiva (efavirenz) is one of the most widely used and effective components of an HIV medication regimen. However, it is not a first-line choice because it can have a lot of side effects.
Upsides
- First-choice treatment for HIV in patients with good kidney function.
- One tablet contains four different HIV medications.
- Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir) is only taken once daily.
- There are assistance programs available through the manufacturer of Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir) if you need help paying for high insurance copays.
- If first-line choices for HIV medications are not an option, Sustiva (efavirenz) would be a good alternative to consider.
- Only taken once daily.
- Sustiva (efavirenz) is available in combination tablets.
- Can be used in patients with mild to moderate kidney damage.
- Can be used in children who are at least 3 months old.
Downsides
- Can't be used in patients with kidney problems.
- Can interact with many other drugs.
- Not suggested for women who plan on becoming pregnant.
- Many people exerience intolerable side effects (eg. insomnia, dizziness, abnormal dreams, confusion), which make it hard to take the medication regularly.
- Cannot be taken alone for treatment of HIV.
Used for
Dosage forms
- Pill
- Pill
Price
Lowest price
$3076.91
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$288.23
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Side effects
9possible side effects
- Nausea16%
- Diarrhea12%
- Abnormal dreams9%
- Headache7%
- Fatigue4%
- Rash4%
- Dizziness3%
- Insomnia3%
- Flatulence2%
19possible side effects
- Skin rash16%
- Diarrhea14%
- Pain13%
- Nausea10%
- Dizziness9%
- Itching9%
- Fatigue8%
- Headache8%
- Insomnia7%
- Vomiting6%
- Trouble concentrating5%
- Depression5%
- Indigestion4%
- Anxiety4%
- Abnormal dreams3%
- Abdominal pain3%
- Sleepiness2%
- Nervousness2%
- Loss of appetite2%
Risks and risk factors
- Lactic acidosis | Enlarged, fatty liver
- Liver disease
- Women
- Obesity
- Cannot be used to treat Hepatitis B Virus (HBV)
- Hepatitis B Virus infection
- Decreased bone mineral density
- History of bone fractures
- Osteoporosis
- Kidney damage
- History of kidney damage
- Taking other medicines that can harm the kidneys
- Immune reconstitution syndrome
- HIV
- Exposure to other infections
- Start of a new HIV medication
- Change in HIV therapy
- Drug interactions
- Taking medicines that interact with Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir)
- Central nervous system (CNS) effects
- Starting Sustiva (efavirenz) for the first few weeks.
- Taking alcohol or other drugs that also affect your nervous system
- Fat redistribution
- HIV treatment
- Liver damage
- History of liver damage
- Alcohol intake
- Immune reconstitution syndrome
- HIV
- Exposure to other infections
- Start of a new HIV medication
- Change in HIV therapy
- Psychiatric effects
- History of mental illness
- History of substance abuse
- Rash
- History of severe skin reactions
- Children