Compare Suboxone vs. Butrans

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT
Treats opioid addiction.

Suboxone (buprenorphine / naloxone) works well to reduce cravings and treat opioid dependence. It's most effective if you have an addiction to heroin or short-acting opioids.

4.0/ 5 average rating with 35 reviewsforSuboxone
Treats severe pain around the clock.

Butrans (buprenorphine) is effective for treating severe pain around-the-clock, but it has a high potential for abuse and misuse.

Upsides
  • Suboxone (buprenorphine / naloxone) works best for people addicted to short-acting opioids or heroin.
  • Your doctor can adjust the dose to a level that controls withdrawal symptoms until you're stable.
  • Suboxone (buprenorphine / naloxone) has fewer side effects and drug interactions compared to other similar medicines.
  • Butrans (buprenorphine) comes in a patch form and only needs to be changed once every 7 days.
  • Butrans (buprenorphine) works around-the-clock to help relieve pain.
  • The Butrans (buprenorphine) patch can be applied on up to 8 different areas of the body.
Downsides
  • Suboxone (buprenorphine / naloxone) is not as good for people who are dependent on long-acting opioids or methadone because of the risk of a long withdrawal.
  • Like all opioids, it can cause slowed breathing, coma, and death from overdose, especially if you mix with other depressants, like pain medicine or alcohol.
  • You have to be very careful with your dose. Changing the size or strength of a film can affect the amount of drug absorbed into your body, and could cause under- or over-dosing.
  • The film can cause reduced sensation in your mouth, painful burning tongue, or burning mouth syndrome.
  • The film may not be appropriate for you if you have lung disease.
  • Butrans (buprenorphine) takes about half a day to start kicking in.
  • Butrans (buprenorphine) has a high potential for misuse and abuse.
  • Butrans (buprenorphine) can cause life-threatening breathing problems, even when used at the correct dose.
  • Older people shouldn't take Butrans (buprenorphine) due to its effects on blood pressure.
  • Other pain relievers may be needed for breakthrough pain.
ADVERTISEMENT
Used for
  • Pain management
Dosage forms
  • Pill
  • Sublingual film
  • Dissolving tablet
  • Patch
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
35 reviews so far
80%
saidit'sworth it
66%
saiditworked well
0%
saidit'sa big hassle

Have you used Suboxone (buprenorphine / naloxone)?

Leave a review
Not enough review data.Leave a review
Side effects
16possible side effects
  • Headache
    36%
  • Withdrawal
    25%
  • Pain
    22%
  • Nausea
    15%
  • Difficulty sleeping
    14%
  • Sweating
    14%
  • Constipation
    12%
  • Stomach pain
    11%
  • Dilation of blood vessels
    9%
  • Chills
    8%
  • Vomiting
    8%
  • Weakness
    7%
  • Infection
    6%
  • Hay fever
    5%
  • Back pain
    4%
  • Diarrhea
    4%
See more detailed side effects
15possible side effects
  • Nausea
    21%
  • Application site itchiness
    15%
  • Dizziness
    15%
  • Headache
    14%
  • Sleepiness
    13%
  • Constipation
    13%
  • Vomiting
    9%
  • Application site redness
    7%
  • Application site rash
    6%
  • Dry mouth
    6%
  • Tiredness
    5%
  • Excessive sweating
    4%
  • Accumulation of fluid in arms and legs
    3%
  • Itching
    3%
  • Stomach discomfort
    2%
See more detailed side effects
Risks and risk factors
  • Low blood pressure
    • Cardiovascular disease
    • dehydration
    • taking drugs that lower blood pressure
  • Liver failure
    • Liver disease
    • Hepatitis B and C
    • Taking Suboxone (buprenorphine / naloxone) with other drugs that cause liver damage
  • Severe allergic reactions
  • Respiratory depression
    • Taking with alcohol or other drugs that slow the nervous system
    • Lung disease
  • Unintentional child exposure
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings
  • Potential for addiction, abuse, and misuse
    • Personal or family history of substance abuse
    • History of mental illness
  • Life-threatening effects on breathing
    • Children
    • Those who overdose on Butrans (buprenorphine)
    • Use with other medications that slow down breathing
  • Harm to fetus or newborn baby
    • Pregnant women who use Butrans (buprenorphine) for a long period of time
  • Interactions with other medicines
    • Taking other medications that also cause sleepiness and/or slow down breathing
  • Severe allergic reaction
  • Risk of possible overdose and death
    • Exposure to the sun or an external source of heat for a long period of time
See more detailed risks and warnings