Compare Suboxone vs. tramadol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats opioid addiction.

Suboxone (buprenorphine / naloxone) works well to reduce cravings and treat opioid dependence. It's most effective if you have an addiction to heroin or short-acting opioids.

4.0/ 5 average rating with 35 reviewsforSuboxone
Treats moderate to severe pain.

Ultram (tramadol) works well for pain. Although it's a little weaker than other opioids, it can still be addictive.

3.4/ 5 average rating with 642 reviewsfortramadol
Upsides
  • Suboxone (buprenorphine / naloxone) works best for people addicted to short-acting opioids or heroin.
  • Your doctor can adjust the dose to a level that controls withdrawal symptoms until you're stable.
  • Suboxone (buprenorphine / naloxone) has fewer side effects and drug interactions compared to other similar medicines.
  • Relieves moderate to severe pain. It has been shown to work as well as other opioid pain medications.
  • Compared to typical opioids, it provides unique pain relief and effects on your mood when taken regularly.
  • Has a lower chance of causing breathing problems compared to other typical opioids.
  • Doesn't cause as much constipation as other opioid pain medicines. Staying hydrated and taking laxatives can help treat this side effect.
Downsides
  • Suboxone (buprenorphine / naloxone) is not as good for people who are dependent on long-acting opioids or methadone because of the risk of a long withdrawal.
  • Like all opioids, it can cause slowed breathing, coma, and death from overdose, especially if you mix with other depressants, like pain medicine or alcohol.
  • You have to be very careful with your dose. Changing the size or strength of a film can affect the amount of drug absorbed into your body, and could cause under- or over-dosing.
  • The film can cause reduced sensation in your mouth, painful burning tongue, or burning mouth syndrome.
  • The film may not be appropriate for you if you have lung disease.
  • Some people think it's weaker than other opioid pain medications. It can also cause more upset stomach.
  • Like other opioid pain relievers, Ultram (tramadol) has a high risk of addiction, abuse, misuse, overdose, and death.
  • The extended release version of Ultram (tramadol) should only be used for severe pain that requires daily, around-the-clock treatment once alternative treatments haven't worked.
  • It's a controlled substance regulated by the federal government. This means that your use of Ultram (tramadol) will be tracked to prevent potential prescription abuse.
  • Like all opioids, don't use when pregnant, since the baby can become dependent on it and have withdrawal symptoms after birth.
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Used for
Dosage forms
  • Pill
  • Sublingual film
  • Dissolving tablet
  • Pill
  • Extended release
  • Extended release capsule
  • Dissolving tablet
Price
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Reviews
35 reviews so far
80%
saidit'sworth it
66%
saiditworked well
0%
saidit'sa big hassle

Have you used Suboxone (buprenorphine / naloxone)?

Leave a review
642 reviews so far
61%
saidit'sworth it
40%
saiditworked well
16%
saidit'sa big hassle

Have you used Ultram (tramadol)?

Leave a review
Side effects
16possible side effects
  • Headache
    36%
  • Withdrawal
    25%
  • Pain
    22%
  • Nausea
    15%
  • Difficulty sleeping
    14%
  • Sweating
    14%
  • Constipation
    12%
  • Stomach pain
    11%
  • Dilation of blood vessels
    9%
  • Chills
    8%
  • Vomiting
    8%
  • Weakness
    7%
  • Infection
    6%
  • Hay fever
    5%
  • Back pain
    4%
  • Diarrhea
    4%
See more detailed side effects
13possible side effects
  • Dizziness
    26%
  • Nausea
    24%
  • Constipation
    24%
  • Headache
    18%
  • Sleepiness
    16%
  • Vomiting
    9%
  • Pruritus
    8%
  • CNS Stimulation
    7%
  • Asthenia
    6%
  • Sweating
    6%
  • Dyspepsia
    5%
  • Dry Mouth
    5%
  • Diarrhea
    5%
See more detailed side effects
Risks and risk factors
  • Low blood pressure
    • Cardiovascular disease
    • dehydration
    • taking drugs that lower blood pressure
  • Liver failure
    • Liver disease
    • Hepatitis B and C
    • Taking Suboxone (buprenorphine / naloxone) with other drugs that cause liver damage
  • Severe allergic reactions
  • Respiratory depression
    • Taking with alcohol or other drugs that slow the nervous system
    • Lung disease
  • Unintentional child exposure
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings
  • Breathing problems
    • Age 65 or greater
    • Overdose
    • Using alcohol, benzodiazepines or other medicines that slow breathing
  • Addiction, abuse, and overdose
    • Taking more than the prescribed dose
    • Taking with alcohol or benzodiazepines
    • Stopping Ultram (tramadol) suddenly
  • Interactions with other drugs
  • Withdrawal in newborns
    • Pregnancy
  • Accidental ingestion
    • Children can reach medication
See more detailed risks and warnings