Compare Sudafed PE Pressure Pain And Cough vs. Alka-Seltzer Plus Day Cold And Flu
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Relieves coughing and cold symptoms.
Sudafed Pe Pressure Pain And Cough (Acetaminophen / Dextromethorphan / Phenylephrine) is good for multiple cold symptoms, but it's more medicine than you need if you only have one symptom.
Relieves cold and flu symptoms.
Alka-Seltzer Plus Day Cold And Flu (Acetaminophen / Dextromethorphan / Phenylephrine) is good for multiple cold symptoms, but it's more medicine than you need if you only have one symptom.
Upsides
- Sudafed Pe Pressure Pain And Cough (Acetaminophen / Dextromethorphan / Phenylephrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
- The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
- The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
- Alka-Seltzer Plus Day Cold And Flu (Acetaminophen / Dextromethorphan / Phenylephrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
- The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
- The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than to other pain medications like aspirin or ibuprofen.
Downsides
- If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
- Phenylephrine doesn't last as long as other oral decongestants like pseudoephedrine.
- You shouldn't use it if you have high blood pressure.
- To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
- If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
- Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
- You shouldn't use it if you have high blood pressure.
- To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it is a very common ingredient in pain and cold/flu combination medicines.
Used for
Dosage forms
- Pill
- Pill
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Side effects
The Sudafed Pe Pressure Pain And Cough (Acetaminophen / Dextromethorphan / Phenylephrine) FDA package insert doesn’t have numbers about how common side effects are.
The Alka-Seltzer Plus Day Cold And Flu (Acetaminophen / Dextromethorphan / Phenylephrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Liver damage
- Taking with alcohol
- Taking with other Tylenol-containing medicines
- History of liver disease
- High blood pressure
- History of high blood pressure
- Taking MAO inhibitors
- Chronic cough from an infection
- History of chronic obstructive pulmonary disease (COPD)
- History of smoking
- Serotonin syndrome
- Using other medications that affect serotonin
- Harm to unborn babies
- Women of childbearing age
- Liver damage
- Drinking more than 2 alcoholic beverages a day
- Taking with other Tylenol-containing medicines
- History of liver disease
- High blood pressure
- History of high blood pressure
- Taking MAO inhibitors
- Chronic cough from an infection
- History of chronic obstructive pulmonary disease (COPD)
- History of smoking
- Serotonin syndrome
- Using other medications that affect serotonin