Compare Sulfasalazine vs. chloroquine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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chloroquine

Prescription only
Reduces inflammation.

Azulfidine (Sulfasalazine) is used to treat moderate to severe inflammatory bowel conditions. It's also used with other medicines to treat rheumatoid arthritis.

Prevents and treats malaria, and also treats a type of bowel infection.

Effectively prevents and treats malaria, and treats a certain type of intestinal infection but can cause serious side effects in certain people.

Upsides
  • Can slow down the progression of your rheumatoid arthritis.
  • Helps control your stomach problems if you're taking it for ulcerative colitis.
  • chloroquine is generally safe to use during pregnancy and for children.
  • You can take chloroquine with or without food.
Downsides
  • Requires constant lab monitoring, at least every other week when you first start using it.
  • Not a good option if you have kidney or liver disease.
  • If you're allergic to sulfa drugs or aspirin, you can't take Azulfidine (Sulfasalazine).
  • Can interfere with lab test results, so let your doctor know if you're taking this drug.
  • Interacts with a lot of different drugs and can also cause many side effects.
  • chloroquine needs to be taken 1-2 weeks before traveling to an area with malaria, compared to some alternatives that can be taken 1-2 days before.
  • chloroquine is only effective against malaria from certain areas of the world.
  • chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
Price
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Reviews
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Side effects
8possible side effects
  • Nausea
    19%
  • Stomach problems
    13%
  • Rash
    13%
  • Headache
    9%
  • Stomach pain
    8%
  • Vomiting
    8%
  • Fever
    5%
  • Dizziness
    4%
See more detailed side effects
The chloroquine FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Kidney, liver, or blood problems
  • Serious skin reactions
  • Serious allergic reactions
  • Serious infections
  • Drug interactions
See more detailed risks and warnings
  • Heart problems
    • Heart problems
  • Muscle weakness
    • Long-term use
  • Low blood counts
    • G6PD (glucose-6-phosphate dehydrogenase) deficiency
  • Eye injury
    • Taking high dose of chloroquine
    • Long-term use
    • Taking tamoxifen
    • Low body weight
    • Kidney problems
  • Liver damage
    • Taking other drugs that affect the liver
    • Alcoholism
    • Liver conditions
  • Hearing damage
    • History of hearing problems
See more detailed risks and warnings