Compare Sustol vs. Sancuso
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Sustol (granisetron) is a long-acting injection that helps to prevent nausea and vomiting due to cancer chemotherapies, but causes bleeding and bruising at the injection site.
Sancuso (granisetron) is a good choice to reduce nausea and vomiting if it's hard for you to take oral medicines, but is very expensive.
- Each dose of Sustol (granisetron) provides relief from nausea and vomiting for at least 7 days.
- Dosing is less frequent than alternatives.
- Injection may be preferrable if you have difficulty swallowing a pill.
- Each Sancuso (granisetron) patch provides around-the-clock relief from nausea and vomiting for up to 7 days without having to re-dose and without problems associated with missing a dose.
- May be a better option for some people on multi-day chemotherapy regimens.
- Sustol (granisetron) must be given at the doctor's office or infusion center 30 minutes before chemotherapy.
- The dose of Sustol (granisetron) needs to be adjusted if you have poor kidney function.
- Available as an expensive, branded product only.
- Must be applied at least 24 hours before the scheduled chemotherapy.
- Sancuso (granisetron) has the possibility of interacting with antidepressants that can result in a dangerous build up of serotonin.
- Must restrict from certain activites such as swimming and strenous excerise while wearing Sancuso (granisetron).
- Should be used with caution in people with any heart condition.
- Prevention of nausea and vomiting due to cancer chemotherapy
- Extended-release injection
- Serotonin syndrome
- Taking other medicines that affect serotonin levels such as anti-depressants
- Troublesome stomach side-effects (ileus)
- Taking other medications that cause constipation such as Norco and Percocet.
- Injection site reactions
- Bruising/bleeding more likely if also taking medications that affect blood coagulation
- Allergic reactions
- Rare serious drug interaction
- Taking other medicines that affect serotonin levels such as tramadol and anti-depressants
- Heart disease
- Masking of intestinal blockage and stomach bloating
- Skin reactions
- Heat exposure
- Exposure to heat
- Sun exposure
- Exposure to sun