Compare Tegretol vs. Depakote
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats seizures and epilepsy.
Tegretol (carbamazepine) is useful for preventing seizures and relieving certain types of nerve pain, but reduces how well many other medications work.
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3.3/ 5 average rating with 61 reviewsforTegretol
Treats and prevents seizures, and stabilizes mood.
Depakote (divalproex) is good for long-term prevention of seizures, manic episodes in bipolar disorder, and migraines.
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3.3/ 5 average rating with 97 reviewsforDepakote
Upsides
- Lowers the frequency of seizures, especially for people with tonic-clonic and partial seizures.
- First-choice option for trigeminal neuralgia (nerve pain involving the face, head, and neck), and can relieve other types of nerve pain.
- Equetro is helpful in stabilizing mood for people with bipolar disorder.
- Available as a generic in many forms: pill, extended-release pill, suspension, and chewable tablet.
- Lowers the frequency of seizures, especially for people with absence seizures or complex partial seizures.
- Depakote (divalproex) is a first-line treatment to stabilize mood for people with bipolar disorder.
- Depakote (divalproex) is helpful for preventing frequent migraines.
- The sprinkle pill can be swallowed whole or can be opened up and mixed with applesauce if you have a hard time swallowing.
- Depakote (divalproex) is available as a generic.
Downsides
- Takes several weeks to feel the full effects.
- Interacts with many other medicines and supplements.
- Higher risk of skin reactions compared to other antiepileptic medicines, ranging from mild to life-threatening rash.
- Requires routine blood tests to see how the medicine is affecting your body.
- Can't take the suspension form with other liquid medications.
- It can take 3 to 4 weeks before you feel the full effects of Depakote (divalproex).
- Depakote (divalproex) is not a good medication for people with liver problems.
- Requires regular blood tests to see how the medication is affecting your body.
- Depakote (divalproex) can make you bleed more easily.
Used for
- Partial seizures
- Generalized tonic-clonic seizures
- Mixed seizure patterns
- Trigeminal neuralgia
- Nerve pain
- Pain
- Agitation
- Depression
- Psychosis
- Alcohol withdrawal syndrome
- Restless legs syndrome
Dosage forms
- Pill
- Extended-release pill
- Suspension
- Chewable tablet
- Pill
- Extended release pill
- Delayed release pill
Price
Lowest price
$34.40
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$29.92
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Reviews
61 reviews so far
56%
saidit'sworth it
43%
saiditworked well
23%
saidit'sa big hassle
Have you used Tegretol (carbamazepine)?
Leave a review97 reviews so far
46%
saidit'sworth it
40%
saiditworked well
27%
saidit'sa big hassle
Have you used Depakote (divalproex)?
Leave a reviewSide effects
The Tegretol (carbamazepine) FDA package insert doesn’t have numbers about how common side effects are.
9possible side effects
- Nausea22%
- Sleepiness19%
- Dizziness12%
- Vomiting12%
- Accidental injury11%
- Feeling weak10%
- Abdominal pain9%
- Upset stomach9%
- Rash6%
Risks and risk factors
- Life-threatening skin reactions
- Carrying HLA-B*1502 gene
- Asian ancestry
- Blood disorders
- Suicidal thoughts or behavior
- History of depression
- Serious allergic reactions
- History of allergic reaction to Trileptal (oxcarbamazepine)
- Pregnancy
- Mental changes due to low sodium
- Age 65 or older
- Dehydration
- Taking diuretics (water pills)
- Harm to fetus
- Liver damage
- Children under age 2
- History of metabolic disorders
- Severe seizure disorder
- Brain disease
- History of liver problems
- Pancreas problems
- Suicidal thoughts or behavior
- History of depression
- Increased bleeding
- Mental changes
- History of metabolic disorders
- People also taking Topamax