Compare thiothixene vs. Abilify

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Navane (thiothixene)

Prescription only

Abilify (aripiprazole)

Prescription only
Treats schizophrenia.

Navane (thiothixene) isn't a first choice for treating schizophrenia because of the side effects, but it is cheaper than other medicines.

Helps control your thoughts and mood.

Abilify (aripiprazole) is good for treating psychosis and mania, and can help with depression. It's less likely to cause side effects than other antipsychotics.

3.2/ 5 average rating with 252 reviewsforAbilify
  • Navane (thiothixene) is available in generic.
  • Navane (thiothixene) is less likely to make you sleepy.
  • Effective at relieving psychotic symptoms and manic episodes.
  • More energizing than other antipsychotics.
  • Fewer side effects than other antipsychotics.
  • Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
  • Available as a generic, which is cheaper.
  • Side effects include weight gain and high blood sugar.
  • Navane (thiothixene) can cause low blood pressure, which can cause fainting or falls if you’re not careful.
  • Smoking tobacco can make Navane (thiothixene) work poorly.
  • Mild risk of extrapyramidal symptoms (EPS), a movement disorder that includes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find the one that works for you and that you can tolerate.
Used for
Dosage forms
  • Pill
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
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252 reviews so far
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Side effects
The Navane (thiothixene) FDA package insert doesn’t have numbers about how common side effects are.
4possible side effects
  • Restlessness
  • Sedation
  • Tremor
  • Difficulty controlling movements
See more detailed side effects
Risks and risk factors
  • Higher risk of death
    • People age 65 or older with dementia and psychosis
  • Difficulty controlling movements
  • Neuroleptic malignant syndrome
  • Drowsiness and sleepiness
    • Drinking alcohol, or taking opioids, benzodiazepines, or sleeping medicines
  • Low blood pressure
See more detailed risks and warnings
  • Increased risk of death
    • Elderly patients with dementia
  • Suicidal thoughts or behavior
    • Age 24 years or younger
    • Use of antidepressant medications
  • Shaking and restlessness
  • Increased blood sugar and cholesterol, and weight gain
    • People with diabetes
    • People with high cholesterol
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
  • Low blood pressure
See more detailed risks and warnings