Compare Topamax vs. Fioricet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT
Prevents seizures and migraine headaches.

Topamax (topiramate) is very effective at preventing many types of seizures and migraines, but it can cause several severe side effects that can lead to stopping the medication.

3.3/ 5 average rating with 56 reviewsforTopamax
Treats tension headaches.

Fioricet (Butalbital / Acetaminophen / Caffeine) works well for tension headaches, but isn’t recommended due to the ability to overuse it and have withdrawal symptoms.

4.3/ 5 average rating with 17 reviewsforFioricet
Upsides
  • Can lower your number of seizures and also prevent migraine headaches. This medicine can be used on its own or with other antiepileptic medicines to lower the frequency of seizures.
  • Doesn't need routine blood tests like similar medications.
  • Available in short-acting and long-acting forms.
  • Comes as a generic, so it's relatively cheap.
  • Fioricet (Butalbital / Acetaminophen / Caffeine) works better and faster in treating tension headaches than the combination of acetaminophen and codeine.
  • Fioricet (Butalbital / Acetaminophen / Caffeine) doesn’t cost much since it's available as a generic medication.
  • Fioricet (Butalbital / Acetaminophen / Caffeine) has very few side effects.
  • It has been widely used for a long time.
Downsides
  • Can cause many severe side effects. People starting Topamax (topiramate) need to be monitored for these effects as soon as they start treatment.
  • This medicine can take 4 to 6 weeks for the full effects of this medication to kick in, especially for people taking it for migraines.
  • Children taking Topamax (topiramate) for long periods of time need to have their dose adjusted by their pediatrician as they grow.
  • At higher doses (ie. 400 mg/day), children may experience difficulty with concentration/attention, fever, flushing, and confusion.
  • Fioricet (Butalbital / Acetaminophen / Caffeine) isn't the first choice medication for treating tension headaches.
  • It's not a good medication for long-term use.
  • Overuse of Fioricet (Butalbital / Acetaminophen / Caffeine) can lead to chronic tension headaches.
  • Fioricet (Butalbital / Acetaminophen / Caffeine) can cause dangerous withdrawal symptoms, intoxication, and dependence.
  • Taking Fioricet (Butalbital / Acetaminophen / Caffeine) can decrease your ability to drive a car, or operate machinery.
ADVERTISEMENT
Used for
Dosage forms
  • Pill
  • Extended release capsule
  • Pill
  • Oral solution
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
56 reviews so far
52%
saidit'sworth it
50%
saiditworked well
36%
saidit'sa big hassle

Have you used Topamax (topiramate)?

Leave a review
17 reviews so far
88%
saidit'sworth it
76%
saiditworked well
12%
saidit'sa big hassle

Have you used Fioricet (Butalbital / Acetaminophen / Caffeine)?

Leave a review
Side effects
39possible side effects
  • Sleepiness
    26%
  • Loss of appetite
    24%
  • Fatigue
    16%
  • Injury
    14%
  • Nervousness
    14%
  • Personality disorder (behavior problems)
    11%
  • Difficulty with concentration/attention
    10%
  • Weight loss
    9%
  • Aggressive reaction
    9%
  • Abnormal gait
    8%
  • Purpura
    8%
  • Difficulty sleeping
    8%
  • Viral infection
    7%
  • Impaired coordination
    6%
  • Nausea
    6%
  • Increased saliva
    6%
  • Muscle spasm
    5%
  • Constipation
    5%
  • Difficulty with memory
    5%
  • Pneumonia
    5%
  • Dizziness
    4%
  • Speech disorders/ related speech problems
    4%
  • Nose bleed
    4%
  • Confusion
    4%
  • Urinary incontinence
    4%
  • Stomach flu
    3%
  • Psychomotor slowing
    3%
  • Skin disorder
    3%
  • Allergic reaction
    2%
  • Abnormal reflexes
    2%
  • Thirst
    2%
  • Pussing
    2%
  • Hair loss
    2%
  • Dermatitis
    2%
  • Increased hair growth
    2%
  • Red skin rash
    2%
  • Eye abnormality
    2%
  • Abnormal vision
    2%
  • Leukopenia
    2%
See more detailed side effects
The Fioricet (Butalbital / Acetaminophen / Caffeine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Suicidal thoughts or behavior
    • History of depression
  • Fever and inability to sweat
    • Children
  • Mental and cognitive changes
    • History of metabolic disorders
    • People also taking Depakote
  • Kidney stones
    • Low-carb diet
    • Dehydration
    • Drug interactions
  • Vision problems
  • Withdrawal seizures
    • Stopping Topamax (topiramate) suddenly
See more detailed risks and warnings
  • Liver damage
    • Drinking more than 2 alcoholic beverages a day
    • Taking with other acetaminophen-containing medicines
    • History of liver disease
  • Hypersensitivity (allergic) reactions
See more detailed risks and warnings