Compare Toujeo vs. Apidra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Toujeo (insulin glargine)

Prescription only
Lowers blood sugar.

Toujeo (insulin glargine) is a concentrated long-actin insulin that allows you to inject higher doses at lower volume compared to other long-acting insulins like Lantus and Levemir.

Controls blood sugar.

Apidra (insulin glulisine) is an insulin that controls blood sugar during your meals, but you'll still have to follow your doctor's diet and exercise plan.

Upsides
  • Most effective medicine for controlling your blood sugar.
  • Can be injected once daily.
  • Contains 3 times as much insulin as other long-acting insulins, which means that you can inject lower fluid volume.
  • Can be used in patients 65 and older.
  • Apidra (insulin glulisine) starts working in as soon as 15 minutes.
  • Programs are available to lower your copay. Talk to your doctor or pharmacist.
  • Can be used in people over 65 and children 4 years of age and older.
Downsides
  • Has to be injected.
  • Can cause weight gain like other insulins
  • Can cause low blood sugar (hypoglycemia), especially if you do not take it consistently or have an inconsistent meal and exercise schedule.
  • Your doctor might have to check your kidneys and liver regularly if you've had kidney or liver problems in the past.
  • Since Apidra (insulin glulisine) is an injectable, it might not be a good treatment option for people who are afraid of needles.
  • Only available as a brand name, so Apidra (insulin glulisine) can be expensive.
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Used for
Dosage forms
  • Injection
  • Injection
Price
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Reviews
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Side effects
3possible side effects
  • Hypoglycemia (low blood sugar)
    69%
  • Common cold
    13%
  • Lung infection
    10%
See more detailed side effects
1possible side effects
  • Common cold
    11%
See more detailed side effects
Risks and risk factors
  • Sharing of Toujeo (insulin glargine) pens
  • Changes in blood sugar levels
    • Changes in insulin
    • Alcohol
    • Other anti-diabetic medications
  • Medication errors
    • Using more than one insulin at a time
  • Severe allergic reactions
    • Allergic reactions to other insulins
  • Hypoglycemia (low blood sugars)
  • Fluid accumulation leading to heart failure
    • Taking thiazolidinediones in combination with insulin
See more detailed risks and warnings
  • Sharing of pen and needles
  • Low blood sugar
    • Changes in diet and exercise
    • Drinking alcohol
    • Taking other medications for diabetes
    • Over age 65
    • Liver or kidney problems
  • Severe allergic reactions
  • Low blood potassium levels
    • Taking laxatives
    • Taking medications that increase urination
  • Mixing of insulins
  • Fluid buildup
    • Taking Avandia or Actos
See more detailed risks and warnings