Compare Toujeo vs. glyburide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Toujeo (insulin glargine)

Prescription only

Diabeta (glyburide)

Prescription only
Lowers blood sugar.

Toujeo (insulin glargine) is a concentrated long-actin insulin that allows you to inject higher doses at lower volume compared to other long-acting insulins like Lantus and Levemir.

Lowers blood sugar.

Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.

3.3/ 5 average rating with 110 reviewsforglyburide
Upsides
  • Most effective medicine for controlling your blood sugar.
  • Can be injected once daily.
  • Contains 3 times as much insulin as other long-acting insulins, which means that you can inject lower fluid volume.
  • Can be used in patients 65 and older.
  • Available as an oral tablet.
  • Lowers your A1c (average blood sugar over time) up to 2%.
  • Available in generic version.
  • Available in single pill combination with other anti-diabetic medicines.
Downsides
  • Has to be injected.
  • Can cause weight gain like other insulins
  • Can cause low blood sugar (hypoglycemia), especially if you do not take it consistently or have an inconsistent meal and exercise schedule.
  • More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
  • You will have to check your blood sugar often when you first start taking it.
  • Can cause weight gain (about 2 to 3 pounds).
  • Not ideal for elderly or those with poor kidney function.
  • May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
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Used for
Dosage forms
  • Injection
  • Pill
Price
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Reviews
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110 reviews so far
45%
saidit'sworth it
34%
saiditworked well
21%
saidit'sa big hassle

Have you used Diabeta (glyburide)?

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Side effects
3possible side effects
  • Hypoglycemia (low blood sugar)
    69%
  • Common cold
    13%
  • Lung infection
    10%
See more detailed side effects
2possible side effects
  • Nausea and heartburn
    2%
  • Skin allergies
    2%
See more detailed side effects
Risks and risk factors
  • Sharing of Toujeo (insulin glargine) pens
  • Changes in blood sugar levels
    • Changes in insulin
    • Alcohol
    • Other anti-diabetic medications
  • Medication errors
    • Using more than one insulin at a time
  • Severe allergic reactions
    • Allergic reactions to other insulins
  • Hypoglycemia (low blood sugars)
  • Fluid accumulation leading to heart failure
    • Taking thiazolidinediones in combination with insulin
See more detailed risks and warnings
  • Low blood sugar
    • Over age 65
    • Kidney problems
    • Use of other blood sugar lowering medicines
    • Alcohol
    • Intense physical activity
  • Severe allergic reactions
    • History of sulfa allergies
See more detailed risks and warnings