Compare Toujeo vs. Humalog

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Toujeo (insulin glargine)

Prescription only

Humalog (insulin lispro)

Prescription only
Lowers blood sugar.

Toujeo (insulin glargine) is a concentrated long-actin insulin that allows you to inject higher doses at lower volume compared to other long-acting insulins like Lantus and Levemir.

Lowers blood sugar.

Humalog (insulin lispro) is a fast-acting insulin that controls blood sugar around meal times.

3.7/ 5 average rating with 280 reviewsforHumalog
Upsides
  • Most effective medicine for controlling your blood sugar.
  • Can be injected once daily.
  • Contains 3 times as much insulin as other long-acting insulins, which means that you can inject lower fluid volume.
  • Can be used in patients 65 and older.
  • Humalog (insulin lispro) is the most effective medication for lowering your blood sugar.
  • Works quickly to control your sugar levels after meals.
  • Dose can be easily adjusted to create a regimen that's tailored to your body's needs.
  • Humalog (insulin lispro) can be used even if you have liver or kidney problems, unlike other anti-diabetic medications.
Downsides
  • Has to be injected.
  • Can cause weight gain like other insulins
  • Can cause low blood sugar (hypoglycemia), especially if you do not take it consistently or have an inconsistent meal and exercise schedule.
  • You have to take Humalog (insulin lispro) by injection.
  • Humalog (insulin lispro) is likely to cause moderate weight gain (around 4 to 6 pounds).
  • There is a higher risk for episodes of low blood sugar compared to other anti-diabetic medications.
  • Effects do not last long enough to control your blood sugar for a whole day.
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Used for
Dosage forms
  • Injection
  • Injection
Price
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Reviews
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280 reviews so far
64%
saidit'sworth it
50%
saiditworked well
16%
saidit'sa big hassle

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Side effects
3possible side effects
  • Hypoglycemia (low blood sugar)
    69%
  • Common cold
    13%
  • Lung infection
    10%
See more detailed side effects
The Humalog (insulin lispro) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Sharing of Toujeo (insulin glargine) pens
  • Changes in blood sugar levels
    • Changes in insulin
    • Alcohol
    • Other anti-diabetic medications
  • Medication errors
    • Using more than one insulin at a time
  • Severe allergic reactions
    • Allergic reactions to other insulins
  • Hypoglycemia (low blood sugars)
  • Fluid accumulation leading to heart failure
    • Taking thiazolidinediones in combination with insulin
See more detailed risks and warnings
  • Life-threatening low blood sugar (hypoglycemia)
    • Insulin dose too high
    • Use of other blood sugar lowering medications
    • Poor injection techniques
  • Complications due to low potassium
    • Use of medications that lower potassium
    • Current electrolyte imbalance
  • Severe allergic reactions
    • Allergy to insulin
See more detailed risks and warnings