Compare Toujeo vs. Januvia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Toujeo (insulin glargine)

Prescription only

Januvia (sitagliptin)

Prescription only
Lowers blood sugar.

Toujeo (insulin glargine) is a concentrated long-actin insulin that allows you to inject higher doses at lower volume compared to other long-acting insulins like Lantus and Levemir.

Lowers your blood sugar.

Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.

3.2/ 5 average rating with 143 reviewsforJanuvia
Upsides
  • Most effective medicine for controlling your blood sugar.
  • Can be injected once daily.
  • Contains 3 times as much insulin as other long-acting insulins, which means that you can inject lower fluid volume.
  • Can be used in patients 65 and older.
  • Oral blood sugar-lowering medicine.
  • Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
  • Uses the hormones naturally produced by your body to affect how sugar is processed.
  • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
Downsides
  • Has to be injected.
  • Can cause weight gain like other insulins
  • Can cause low blood sugar (hypoglycemia), especially if you do not take it consistently or have an inconsistent meal and exercise schedule.
  • Lowers A1c (average blood sugar over time) by less than 1%.
  • Available as brand version only.
  • Some people might get frequent cold-like symptoms.
  • Rare but serious side effects include pancreatitis and severe joint pain.
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Used for
Dosage forms
  • Injection
  • Pill
Price
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Reviews
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143 reviews so far
44%
saidit'sworth it
34%
saiditworked well
17%
saidit'sa big hassle

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Side effects
3possible side effects
  • Hypoglycemia (low blood sugar)
    69%
  • Common cold
    13%
  • Lung infection
    10%
See more detailed side effects
3possible side effects
  • Common cold
    5%
  • Diarrhea
    3%
  • Abdominal pain
    2%
See more detailed side effects
Risks and risk factors
  • Sharing of Toujeo (insulin glargine) pens
  • Changes in blood sugar levels
    • Changes in insulin
    • Alcohol
    • Other anti-diabetic medications
  • Medication errors
    • Using more than one insulin at a time
  • Severe allergic reactions
    • Allergic reactions to other insulins
  • Hypoglycemia (low blood sugars)
  • Fluid accumulation leading to heart failure
    • Taking thiazolidinediones in combination with insulin
See more detailed risks and warnings
  • Death from inflammation of the pancreas (pancreatitis)
    • History of pancreatitis
    • High blood triglyceride levels
    • Gallstones (stones in gallbladder)
    • History of alchoholism
    • Kidney problems
  • Serious allergic reactions
  • Kidney damage
    • Pre-existing kidney damage
  • Low blood sugar (hypoglycemia)
    • Taking medicines for diabetes
  • Severe joint pain and swelling
See more detailed risks and warnings